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1,533 recruiting studies matching your filters

P2Y12 Inhibitor Versus Aspirin Monotherapy in Patients Undergoing Elective Screening and Surveillance Colonoscopy

Patients on dual antiplatelet therapy )aspirin plus a P2Y12 inhibitor \[clopidogrel, prasugrel, or ticagrelor\]) undergoing screening or surveilance colonoscop…

Coronary Arterial Disease (CAD)Peripheral Vascular Disease

Estimated

~$10 – $6,250

Ochsner Health SystemNCT06613191

Phase 2

A Phase II Study of Reduced Intensity Conditioning in Pediatric Patients and Young Adults ≤55 Years of Age With Non-Malignant Disorders Undergoing Umbilical Cord Blood, Bone Marrow, or Peripheral Blood Stem Cell Transplantation

The objective of this study is to evaluate the efficacy of using a reduced-intensity condition (RIC) regimen with umbilical cord blood transplant (UCBT), doubl…

Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more

Estimated

~$10 – $7,500

Paul SzabolcsNCT01962415

Phase 3

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II)

The objective of this study is to prospectively compare decongestive therapy administered by the Reprieve System to Optimal Diuretic Therapy (ODT) in the treat…

Acute Decompensated Heart Failure

Estimated

~$10 – $8,750

Reprieve Cardiovascular, IncNCT06898515

Phase 1

A Phase 1, Randomized, Placebo-Controlled, First-in-Human, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Orally Administered KT-579 in Healthy Adult Participants

This is a first-in-human study to evaluate safety and tolerability, pharmacokinetics, and pharmacodynamics of single and multiple dose levels of KT-579 in heal…

Healthy Participants

Estimated

~$10 – $8,750

Kymera Therapeutics, Inc.NCT07412288

Phase 1

A Phase 1, Open Label, Multiple Ascending Dose Study to Assess Safety and Tolerability of STM-01 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

A Phase 1, Open label, Multiple Ascending Dose Study to Assess Safety and Tolerability of STM-01 in Participants with Heart Failure with Preserved Ejection Fra…

Heart Failure With Preserved Ejection Fraction (HFpEF)

Estimated

~$10 – $8,750

Secretome TherapeuticsNCT06560762

Observational

Cardiac Resynchronization Therapy Using His/Left Bundle Branch Pacing vs Biventricular Pacing With a Left Ventricular Epicardial Lead in Patients With Heart Failure (HF) With Left Ventricular Ejection Fraction (LVEF)≤50% and With Either a Wide QRS Complex (>130 ms) or With/Anticipated >40% Pacing Randomized Clinical Trial

The investigators aim to prospectively test the comparative effectiveness of His or Left bundle branch pacing in relation to patient centered outcomes (quality…

Heart FailureHeart Failure With Reduced Ejection FractionAV Block+4 more

Estimated

~$10 – $6,250

Baylor College of MedicineNCT05650658

Observational

Healthy Living Anson

The goal of this randomized delayed control intervention research study is to see if participants who receive education and healthy prepared meals improve the …

Obesity (Disorder)Diabetes Type 2Heart Disease+3 more

Estimated

~$10 – $6,250

University of North Carolina, Chapel HillNCT07126587

Phase 1

Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors, Ketones, and Cardiovascular Benefit Research Plan

The study team will examine the effects of SGLT2i (and SGLT2i-induced increases in plasma ketone concentrations) on skeletal muscle and cardiac ketone uptake, …

Type2 DiabetesHeart Failure With Preserved Ejection Fraction

Estimated

~$10 – $6,250

The University of Texas Health Science Center at San AntonioNCT05057806

Phase 4

Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee Osteoarthritis

This is a clinical trial of people who have pain due to knee osteoarthritis at Northwestern University Feinberg School of Medicine. The study will last for abo…

Knee Osteoarthritis

Estimated

~$10 – $6,250

Northwestern UniversityNCT06245109

Phase 2

Evaluation of Ultralow Dose PET Imaging for Detecting 18F-NaF Uptake

The goal of this clinical trial is to evaluate an investigational ultralow dose positron emission tomography (PET imaging) technique for increased bone turnove…

Healthy VolunteerBone AlterationBone and Joint Cancer+2 more

Estimated

~$10 – $7,500

Akiva MintzNCT07284563

Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation: A Prospective Multicenter Study

Heart failure and atrial fibrillation are two of the most common heart diseases globally. Nearly half of all patients with heart failure also have atrial fibri…

Heart Failure (HF)Atrial Fibrillation (AF)

Estimated

~$10 – $750

Oslo University HospitalNCT07436299

Observational

Effectiveness and Efficacy of a Ketogenic or Carnivore (Lion) Diet for Quality Life and Symptom Burden in Individuals With Symptomatic Inflammatory Bowel Disease or Rheumatoid Arthritis: A Randomized Controlled Clinical Trial

This study is a randomized controlled clinical trial evaluating whether two therapeutic dietary approaches - a ketogenic diet and a carnivore (lion) diet - can…

Rheumatoid Arthritis (RA)Crohn's Disease (CD)Ulcerative Colitis (UC)

Estimated

~$10 – $6,250

Fuller Research FoundationNCT07524244