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1,574 recruiting studies matching your filters

Pulse Arrival Time as an Alternative Biomarker to Detect Lower-Extremity Peripheral Artery Disease

1\) The purpose of this study is to assess segmental pulse arrival time (PAT) as an alternative biomarker to detect lower-extremity peripheral artery disease (…

Peripheral Artery Disease (PAD)

Estimated

~$10 – $6,250

University of NebraskaNCT07226193

An Open Label, Multi-Center, Retrospective and Prospective Evaluation of Shoulder Arthroplasty Clinical and Radiographic Outcomes

The objective of this study is to collect and evaluate long-term clinical and radiographic outcomes data in order to better understand the safety and performan…

Osteo Arthritis ShouldersOsteonecrosisRotator Cuff Tears+6 more

Randomized, Prospective, Double Blind, Multi-Center, Phase 3 Pivotal Clinical Trial to Compare Efficacy and Safety of CARTISTEM® and Surgical Comparator in Subjects With Knee Cartilage Lesions and Osteoarthritis

To establish the efficacy and safety of CARTISTEM®, a combination product composed of allogeneic human umbilical cord blood-derived mesenchymal stem cells (hUC…

Knee Cartilage Defects

Estimated

~$10 – $8,750

Medipost, Inc.NCT07339111

Clinical Evaluation of Using NIRSense Sensor Patch to Measure Microvascular Perfusion Responses and Predict Decompensation in Cardiogenic Shock Patients

This is a prospective, single-center, observational pilot study of the investigational NIRSense Tissue Oximetry Sensor System (Envello Core), a noninvasive wea…

Cardiogenic ShockAcute Myocardial InfarctionAcute Decompensated Heart Failure

Estimated

~$10 – $1,050

NIRSense Inc.NCT07825363

Observational

Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart Failure (PATRIOT-HF) (QUE 25-018)

Many Veterans who are hospitalized with heart failure do not receive all the recommended heart medications at the right doses before they leave the hospital or…

Heart FailureHeart Failure, Systolic

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT07714239

Phase 1

A Phase 1, Open-Label, Crossover Study to Evaluate the Relative Bioavailability of Different Oral Formulations of KT-621 in Healthy Adult Participants

This is a Phase I study to evaluate the relative bioavailability and safety and tolerability of different oral formulations of KT-621 in healthy adult particip…

Healthy Participants

Estimated

~$10 – $8,750

Kymera Therapeutics, Inc.NCT07823205

Phase 3

A Phase 3, Randomized, Double-Blind, Placebo-controlled, Multicenter, Parallel-group Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder in Participants With Pulmonary Arterial Hypertension

The primary objective of this study is to evaluate the effect of 24-weeks of once daily treatment with TPIP compared with placebo on exercise capacity in adult…

Pulmonary Arterial Hypertension

Estimated

~$10 – $8,750

Insmed IncorporatedNCT07481981

An Open Label, Multi-Center, Single Arm Prospective Evaluation of Exactech Vantage Total Ankle System

The objectives of this study are to evaluate the performance and safety of the Vantage Total Ankle System. This study will follow subjects for a period of up t…

Ankle Rheumatoid ArthritisArthritis of AnkleFailure, Prosthesis

Estimated

~$10 – $1,125

ExactechNCT05619588

Personalized Environment and Genes Study

Despite the overwhelming focus on genetic and genomic causes of human disease over the past two decades, it has been estimated that genetics is currently known…

DiabetesHeart DiseaseAsthma

Estimated

~$10 – $675

National Institute of Environmental Health Sciences (NIEHS)NCT00341237

Phase 1

A Phase I, Randomized, Single-dose, Crossover, 2-Period, Open-Label Study to Assess the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants

The purpose of this study is to measure the pharmacokinetics (PK-how the body processes the study drug) of elecoglipron in healthy participants when taken by m…

Healthy Participants

Estimated

~$10 – $7,500

AstraZenecaNCT07723833

Observational

Randomized, Controlled, Multi-center, Prospective Trial to Assess the Efficacy and Safety of an Anatomic Total Shoulder System.

This study is designed to show that the clinical performance of Mirror Anatomic Shoulder Prosthesis meets the performance of currently marketed device in terms…

Shoulder ArthroplastyTotal Shoulder Arthroplasty

Estimated

~$10 – $7,500

Medacta USANCT07812324

Phase 3

A Randomized, Blinded, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Oral LPCN 1154A in Women With Postpartum Depression

The purpose of this research study is to test the study drug, LPCN 1154A, as a possible treatment for postpartum depression (PPD). The trial aims to determine:…

Depression, PostpartumPostpartum Depression (PPD)Post-partum Depression+3 more

Estimated

~$10 – $8,750

Lipocine Inc.NCT07822321