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1,533 recruiting studies matching your filters

Use of Single-Dose Oral Methadone for Pain Management in Outpatient Arthroscopic Hip and Knee Procedures

The goal of this clinical trial is to learn if oral methadone given before surgery works to minimize post-operative pain and opioid usage. The main questions i…

Arthroscopic Knee RepairArthroscopic Hip Repair

Estimated

~$10 – $6,250

Keck School of Medicine of USCNCT06351215

Observational

Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY

This is an international prospective, multicentre, unblinded, randomised-controlled trial. The primary aim is to assess a targeted screening strategy to detect…

Heart FailureCardiovascular Diseases

Estimated

~$10 – $7,500

NHS Greater Glasgow and ClydeNCT05919342

Phase 1

A Phase 1, Randomized, Double-Blind, Sponsor-Open, Placebo Controlled, First in Human Study to Evaluate the Safety, Tolerability, Immunogenicity, and Pharmacokinetics of Single Ascending and Multiple Doses of PRX019 in Healthy Adults

The purpose of this study is to assess the safety and tolerability of PRX019 in healthy adult participants.

Healthy Participants Study

Estimated

~$10 – $8,750

Prothena Biosciences Ltd.NCT06699680

Phase 4

The Efficacy of Platelet Rich Plasma Compared With Corticosteroid Injections for the Treatment of Pain Associated With Hip Osteoarthritis

Prospective, single-center that may go on to being multicenter, randomized trial comparing platelet rich plasma (PRP) versus corticosteroid injection for the t…

Hip Osteoarthritis

Estimated

~$10 – $7,500

LifeBridge HealthNCT06793982

Phase 4

A Trial Comparing the Effectiveness and Tolerability of Medications in Older Adults With Stable Angina and Multiple Chronic Conditions: LIVEBETTER

To establish the effectiveness and tolerability of standard of care anti-anginal treatment (beta-blocker and calcium channel blocker medications) in older adul…

AnginaStable Ischemic Heart Disease

Estimated

~$10 – $6,250

Yale UniversityNCT05786417

Phase 3

NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis: A Randomized, Controlled Trial

The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanc…

Thumb Osteoarthritis

Estimated

~$10 – $6,250

Mayo ClinicNCT05992883

Post-Market Clinical Follow-up Registry to Evaluate the Safety and Performance of the Atrium Advanta VXT and Flixene Vascular Grafts in Patients Undergoing Surgical Repair or Replacement of Peripheral Arteries

The purpose of the registry is to evaluate the long-term safety and performance of Advanta VXT and Flixene vascular grafts for repair or replacement of periphe…

Peripheral Arterial Disease

Estimated

~$10 – $1,050

Atrium Medical CorporationNCT07161583

Observational

ACHIEVE GREATER: Addressing Cardiometabolic Health In Populations Through Early Prevention in the Great Lakes Region

This project is part of the ACHIEVE GREATER (Addressing Cardiometabolic Health In Populations Through Early Prevention in the Great Lakes Region) Center (IRB 1…

Coronary Heart Disease

Estimated

~$10 – $6,250

University Hospitals Cleveland Medical CenterNCT05918380

Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry

Patients are being asked to be in this research study because medical researchers hope that by gathering information about a large number of children with pulm…

Pulmonary Vascular DiseasePulmonary Arterial Hypertension

Estimated

~$10 – $750

New York Medical CollegeNCT02249923

Phase 2

Endocardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment: A 26-Week (With 26 Week Extension) Phase 2b Randomized, Multi-Center, Double-Blind, Sham Controlled Study to Evaluate Efficacy and Safety

This is a two-part study, comprised of an initial open-label run-in phase (Part 1) in a subset of 3 subjects to provide first data regarding safety, and feasib…

Refractory AnginaCoronary Artery Disease

Estimated

~$10 – $8,750

XyloCor Therapeutics, Inc.NCT07048808

Observational

Initiation and Titration of Guideline Directed Medical Therapy in Heart Failure Cardiogenic Shock With Impella 5.5 for Cardiac Recovery: INTeGRATE

The study will evaluate the impact of a combined device-drug strategy with Impella 5.5 with best practices and optimized GDMT on heart recovery outcomes in pat…

Heart FailureCardiogenic ShockReduced Ejection Fraction Heart Failure

Estimated

~$10 – $8,750

Abiomed Inc.NCT06965504

Phase 1

Phase 1b Open-Label, Multi-Center, Randomized Trial to Evaluate the Safety of PEP and EUFLEXXA for the Treatment of Subjects With Knee Osteoarthritis (KOA)

Evaluate the safety and exploratory efficacy of single intra-articular injections of PEP reconstituted with 0.9% Normal Saline at a low dose (one vial PEP) and…