The investigators are conducting a pilot open-label pre/post interventional trial in adolescents and adults with cystic fibrosis (CF) and abnormal glucose tole…

Cystic Fibrosis Related DiabetesCystic Fibrosis (CF)Abnormal Glucose Tolerance

~Estimated

~$10 – $6,250

Rhode Island HospitalNCT07688070

Phase 2

Effect of GLP-1 Agonist Therapy on Insulin Secretion in Adults With Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a Randomized, Open-label, Cross-over Trial

Diabetes is a major co-morbidity in pancreatic insufficient cystic fibrosis (PI-CF) and associated with worse outcomes. While reduced β-cell mass contributes t…

Cystic FibrosisPancreatic InsufficiencyAbnormal Glucose Tolerance+1 more

~Estimated

~$10 – $6,250

University of PennsylvaniaNCT04731272