The purpose of this study is to find out whether combining inotuzumab and blinatumomab is a safe and effective treatment for participants with newly diagnosed …

B-cell Acute Lymphoblastic LeukemiaB-Cell Acute Lymphoblastic Leukemia, AdultB-ALL

~Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT07313852

Phase 1

Phase I, First in Human, Open Label Study to Evaluate Safety and Tolerability of TRX103 Cells in Subjects With Hematological Malignancies Undergoing HLA-mismatched Related or Unrelated Hematopoietic Stem Cell Transplantation (HSCT)

The purpose of this Phase 1, first in human open-label study is to assess the safety and tolerability of TRX-103 in patients with hematological malignancies un…

Hematologic MalignancyGvHDGVHD,Acute+8 more

~Estimated

~$10 – $8,750

Tr1X, Inc.NCT06462365

Phase 2

Lymphodepleting Chemotherapy With Fludarabine and Cyclophosphamide Prior to Infusion of CAR T Cell Therapy in Patients With Moderate-Severe Renal Dysfunction

This is a prospective, descriptive study designed to assess the feasibility of administering CAR T therapy among patients with moderate to severe renal impairm…

Non-hodgkin Lymphoma,B CellMultiple MyelomaAcute Lymphoblastic Leukemia, Adult

~Estimated

~$10 – $6,250

Northside Hospital, Inc.NCT05909059