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Cognitive Behavioral Therapy for Insomnia in Older African American Adults
Sleep problems, like insomnia, are common in older African Americans. About 25% of older adults in the US have at least 2 symptoms of insomnia, such as having …
Phase 1 Study of LGW16-03 To Identify Nerves
The primary goal of this study is to determine the safety and tolerability of LGW16-03, a novel nerve-labeling fluorophore, in participants undergoing open-fie…
A Pilot Randomized Controlled Trial of a Social Network Intervention for Older Patients With Cancer
This is a pilot randomized controlled trial to assess the feasibility, acceptability, appropriateness, and structure of the SONATA intervention. In addition, i…
Optimization of Care and Recovery in Older Colorectal Surgery Patients: A Hybrid Effectiveness-Implementation Pilot Study Protocol
The goal of this study to test if a care transition intervention designed for older colorectal surgery patients would improve outcomes after discharge. It will…
Controller Development to Enable Individualized Assistance in Robotic Ankle Exoskeletons
This study is developing and testing a new controller for a robotic ankle exoskeleton (Biomotum) that can adjust itself in real time to better support people w…
Restorative Neurophysiology: Feasibility of "Backup and Restore" Technologies for Brains and Bodies
Study to examine the extent to which neurophysiological states recorded for a specific person on one day can be induced on a subsequent day
A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALV-100 in Participants With Overweight or Obesity With or Without Type 2 Diabetes
A Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants with or without Type 2 Diabetes
Supportive Training After Cardiac Rehabilitation Including Virtual Engagement: The STRIVE Study
The proposed research seeks to determine whether virtual coaching and social support focusing on key social cognitive factors will be an effective strategy for…
Improving Needs Among Older Adults: the ICUconnect 2 Primary Palliative Care RCT
Millions of older adults receive care in intensive care units (ICUs) annually. However, the quality and accessibility of ICU-based palliative care is highly va…
Improving Exercise Adherence With App Technology for At-Risk Adults Living in Rural Kansas and Nebraska
Alzheimer's disease and related dementias are a public health crisis impacting individuals across the world. In the United States, adults living in rural areas…
Tracing the Metabolic Flux of Orally Administered NAD+ Precursors in Healthy Young and Older Adults
We are doing this research to learn how healthy younger and older adults use two forms of vitamin B3-called nicotinamide mononucleotide (NMN) and nicotinamide …
Making Intergenerational Connections Through Arts
The purpose of the study is to evaluate the impact on older adults' wellbeing of participating in a 10-week conversation about arts and culture with an interna…