This phase I trial tests the safety, side effects, and best dose of FH-FOLR1 ST chimeric antigen receptor (CAR) T cells and how well they work in treating pati…

Advanced OsteosarcomaRecurrent OsteosarcomaRefractory Osteosarcoma

~Estimated

~$10 – $6,250

Fred Hutchinson Cancer CenterNCT07227571

Phase 1

Phase I/II Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

To find a recommended dose of donated NK cells that can be given with lymphodepleting chemotherapy to patients with advanced renal cell carcinoma, mesothelioma…

Advanced Renal Cell CarcinomaAdvanced MesotheliomaAdvanced Osteosarcoma

~Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT05703854

Phase 2

A Phase 2 Trial of Atezolizumab and Cabozantinib in Adolescents and Young Adults With Recurrent/Metastatic Osteosarcoma (TACOS)

This phase II trial studies the effect of atezolizumab and cabozantinib in treating adolescents and young adults with osteosarcoma that has come back (recurren…

Locally Advanced OsteosarcomaMetastatic OsteosarcomaRecurrent Osteosarcoma+2 more

~Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT05019703