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8 recruiting studies matching your filters

GU-228: Mycophenolate Mofetil in Combination With Prednisone as First-line Treatment of Immune Related Hepatitis Resulting From Checkpoint Inhibitor Therapy

This phase II study evaluates whether early treatment with mycophenolate mofetil (MMF) plus prednisone improves liver inflammation caused by immune checkpoint …

Immune-mediated HepatitisImmune-related Adverse Event

Estimated

~$10 – $6,250

Fox Chase Cancer CenterNCT07663422

A Phase 1 Pharmacokinetic Study of Therapeutic Plasma Exchange for Severe Immune-Related Adverse Events From Immune Checkpoint Inhibitors

The purpose of this study is to characterize the pharmacokinetics of one or more ICIs during and after TPE/PLEX in patients with severe irAEs.

Immune-related Adverse Event

Estimated

~$10 – $750

University of ChicagoNCT07756242

Phase 4

Indomethacin vs. no Indomethacin for Patients Undergoing Biliary ERCP With Prior Biliary Sphincterotomy

This study is a randomized clinical trial evaluating the efficacy of rectal indomethacin in preventing post-endoscopic retrograde cholangiopancreatography (ERC…

Pancreatitis BiliaryPancreatitis Acute BiliaryPancreatitis+3 more

Estimated

~$10 – $5,625

University of California, San FranciscoNCT07661498

CRICKET: Critical Events in Anaesthetised Kids Undergoing Tracheal Intubation

The investigators' overall objective is to assess the incidence of critical events related to tracheal intubation at all international study sites. Furthermore…

Intubation ComplicationAdverse Events

Estimated

~$10 – $1,125

Thomas RivaNCT05804188

Observational

Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions

This study aims to predict and minimize post-discharge adverse events (AEs) during care transitions through early identification and escalation of patient-repo…

Multiple Chronic ConditionsAdverse Event

Estimated

~$10 – $6,250

Brigham and Women's HospitalNCT05282654

Observational

Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences (I-SHARE)

Hospitals ineffectively examine the safety of their processes by relying on voluntary incident reporting (VIR) by clinical staff who are overworked and afraid …

Family Reported Errors and Adverse EventsHealth DisparitiesFamily Safety Reporting+3 more

Estimated

~$10 – $6,250

Boston Children's HospitalNCT05407129

Phase 1

A Non-Interventional Pragmatic Clinical Trial of NLP Models for the Detection of Immune-Related Adverse Events

Immunotherapies have improved cancer outcomes, but have a unique profile of immune-related adverse events (irAEs). Biorepositories have been established to col…

MalignancyImmune Related Adverse Events

Estimated

~$10 – $6,250

Brigham and Women's HospitalNCT06789601

Phase 4

Safety of Simultaneous Administration of Respiratory Syncytial Virus (RSV) Preventive Monoclonal Antibody With Routine Childhood Immunizations in Infants

This is a prospective, randomized, open-label clinical trial to evaluate the safety of administration of respiratory syncytial virus (RSV) preventive monoclona…

FeverAdverse Event Following Immunisation

Estimated

~$10 – $6,250

Duke UniversityNCT07158814