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1,512 recruiting studies matching your filters

Feasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®

This is a feasibility study to determine the usefulness of a brachytherapy device that utilizes active components (palladium-103) of standard devices in a nove…

Lung CancerLung Cancer Stage ILung Cancer Stage II

Estimated

~$10 – $7,500

CivaTech OncologyNCT03290534

Phase 2

A Combination Therapy Strategy to Prevent Anti-PD-1 Therapy Resistance in Metastatic Ovarian Cancer Patients

This is an open label, non-randomized, 2-stage phase II, single arm study to determine the efficacy of New York esophageal squamous cell carcinoma 1 (NY-ESO-1)…

Ovarian Cancer Stage IVOvarian Cancer Stage IIIOvarian Cancer Stage 3

Estimated

~$10 – $6,250

Georgetown UniversityNCT05479045

Observational

weSIPsmarter: An Adaptation and Efficacy Trial to Evaluate a Behaviorally Based Digital Health Intervention Aimed at Reducing Sugary Drinks Among Rural Head Start Preschoolers and Their Parents

This study will include 12 rural Head Start programs, randomly assigned to one of two groups: weSIPsmarter vs. control. The main goal is to find out if weSIPsm…

Sugary Beverages

Estimated

~$10 – $6,250

University of VirginiaNCT07046351

Phase 4

Improving Pain Control in Paraesophageal Hernia Repair: Intravenous Lidocaine Versus Placebo

We aim to study the impact of perioperative IV lidocaine on postoperative pain control in patients undergoing paraesophageal hernia repair. This is in the cont…

Hernia, Paraesophageal

Estimated

~$10 – $6,250

Wake Forest University Health SciencesNCT04096170

The Sleep After Breast Cancer (ABC) Study - Examining Sleep Changes and Biomarkers Among Breast Cancer Patients

This study is being done to learn more about breast cancer patients' experiences with sleep changes during cancer treatment, identify possible reasons for poor…

Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8+2 more

Estimated

~$10 – $750

Ohio State University Comprehensive Cancer CenterNCT07341503

Phase 2

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

This randomized, placebo-controlled trial aims to assess the feasibility, acceptability, and preliminary efficacy of memantine and the University of Carolina (…

Breast CancerLocally Advanced Breast CancerCognitive Impairment+5 more

Estimated

~$10 – $6,250

UNC Lineberger Comprehensive Cancer CenterNCT06727773

Phase 3

Prospective Observational Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

This trial has two cohorts of patients with human epidermal growth factor receptor (HER)-2-positive breast cancer that has spread to other places in the body. …

CardiotoxicityHER2/Neu PositiveMetastatic Malignant Neoplasm in the Brain+2 more

Estimated

~$10 – $7,500

SWOG Cancer Research NetworkNCT03418961

Biomarkers and Dysplastic Respiratory Epithelium

RATIONALE: Studying samples of sputum and tissue in the laboratory from patients with dysplasia or cancer may help doctors identify and learn more about biomar…

Esophageal CancerHead and Neck CancerLung Cancer+1 more

Estimated

~$10 – $750

University of Colorado, DenverNCT00900419

The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic Cancer

Aberrant miRNA production has been linked to a wide range of human cancers and shown to play important roles in their genesis and growth. These miRNA can be de…

Pancreatic Cancer Stage IIIPancreatic Cancer Stage IVPancreatic Ductal Adenocarcinoma+1 more

Estimated

~$10 – $1,125

Nuvance HealthNCT04406831

Phase 2

TRUDI: A Phase II Study of Neoadjuvant Trastuzumab Deruxtecan and Durvalumab for Stage III, HER2-expressing Inflammatory Breast Cancer

The purpose of this study is to test the safety and effectiveness of an investigational drug combination (trastuzumab deruxtecan and durvalumab) to learn wheth…

Invasive Breast CancerInflammatory Breast Cancer Stage IIIHER2-positive Breast Cancer+2 more

Estimated

~$10 – $7,500

Filipa Lynce, MDNCT05795101

Phase 1

Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

The first phase of this study was an open label, randomized pilot study. Enrollment for this phase is now complete. The second phase is a single arm phase 1 s…

Early Stage Non-Small Cell Lung Cancer

Estimated

~$10 – $6,250

Abramson Cancer Center at Penn MedicineNCT03546829

Hemophilia A Research Program (HARP): An Observational Intergenerational Cohort Study of Hemophilia A and Factor VIII Immunogenicity

This study longitudinally observes the intergenerational (mother-child) continuum in hemophilia A from pregnancy through early childhood. Because the study fol…

Hemophilia AHemophilia A, SevereFactor VIII (FVIII)+10 more

Estimated

~$10 – $750

University of WashingtonNCT07414511