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Duke APOL1 Research Biorepository

The Duke ApoL1 Nephropathy Biorepository aims to address needs within non-diabetic kidney failure research by utilizing existing and, when necessary, developin…

End Stage Kidney Disease

Estimated

~$10 – $750

Duke UniversityNCT04160507

Observational

A Pilot Feasibility Study of Vagustim™ Transcutaneous Auricular Vagus Nerve Stimulation Devices

Transcutaneous auricular vagus nerve stimulation (taVNS) has become a therapy of interest for treating chronic immune-medicated illnesses in adults and childre…

Healthy Controls Group - Age and Sex-matched

Estimated

~$10 – $7,500

Northwell HealthNCT07791290

Phase 1

A Phase I Open-label, Multi-center Study to Evaluate the Safety, Tolerability, Dosimetry, and Preliminary Activity of [177Lu]Lu-DWJ155 and Safety and Imaging Properties of [68Ga]Ga-DWJ155 in Patients With Solid Tumors

The purpose of this phase I study is to evaluate the safety, tolerability, dosimetry, and preliminary anti-tumor activity of \[177Lu\]Lu-DWJ155 and the safety …

Breast CancerNon-small Cell Lung Cancer (NSCLC)Gastric/Gastroesophageal Junction (GEJ) Cancer+1 more

Estimated

~$10 – $8,750

Novartis PharmaceuticalsNCT07660055

Observational

Phase 1a/b Trial of Exercise as Interception Therapy for Primary High-Risk Cancer

Researchers think that exercise may be able to prevent cancer from coming back by lowering ctDNA levels. The purpose of this study is to explore how aerobic ex…

Breast CancerProstate CancerColorectal Cancer+9 more

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT04589468

Phase 2

Dynamic Assessments of Molecular Response to Guide Early 177Lu-PSMA-617 Treatment Discontinuation: The DYNAMO Study

This clinical trial studies whether measuring circulating tumor deoxyribonucleic acid (ctDNA) tumor fraction (TF) can be used to help guide the early stopping …

Metastatic Castration-Resistant Prostate AdenocarcinomaStage IVB Prostate Cancer AJCC v8

Estimated

~$10 – $6,250

University of WashingtonNCT07698535

ObservationalRemote eligible

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

The goal of this clinical trial is two-fold. First to investigate the feasibility of whether a remotely administered smartphone app can increase the volume and…

Parkinson DiseaseProdromal StageNeurodegenerative Diseases+8 more

Estimated

~$10 – $6,250

Radboud University Medical CenterNCT06993142

Phase 1

Phase Ib Active Immunotherapy Trial (Expansion) With a Combination of Two Chimeric (Trastuzumab-like and Pertuzumab-like) HER-2 B Cell Peptide Vaccine Emulsified in ISA 51 Adjuvant in Patients With Advanced Solid Tumors

This phase I trial studies the side effects and best dose of vaccine therapy in treating patients with metastatic solid tumors. Vaccines made from antibodies a…

Metastatic Breast CancerHER2-positive Breast CancerEGFR Overexpression+2 more

Estimated

~$10 – $7,500

Pravin T.P KaumayaNCT06414733

Observational

Novel Application of RADA16 Hydrogel in Reducing Sinonasal Morbidity After Endoscopic Skull Base Surgery

The purpose of this study is to specifically evaluate the effectiveness of PuraGel, a RADA16 polypeptide hydrogel, in expediting post-operative healing and re-…

Skull Base NeoplasmsCerebrospinal Fluid LeakageNasal; Hypertrophy, Mucous Membrane (Septum)

Estimated

~$10 – $6,250

Indiana UniversityNCT05898074

GSDIa Disease Monitoring Program

The main objective of this observational study is to evaluate the long-term safety and effectiveness of DTX401 for at least 10 years after DTX401 administratio…

Glycogen Storage Disease Type Ia

Estimated

~$10 – $1,050

Ultragenyx Pharmaceutical IncNCT06636383

Phase 2

(PRESTO) A Randomized Phase II Trial Evaluating Hotspots in Stereotactic Ablative Radiotherapy for Early-Stage Non-Small Cell Lung Cancer

This clinical trial compares stereotactic ablative radiotherapy (SBRT) with hot spots to standard of care SBRT for the treatment of patients with early-stage n…

Early Stage Lung Non-Small Cell CarcinomaStage I Lung Cancer AJCC v8Stage II Lung Cancer AJCC v8

Estimated

~$10 – $7,500

Roswell Park Cancer InstituteNCT07718672

Phase 2

A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Safety, Tolerability, and Serum Phosphate Lowering Effect of Fixed Dose AP306 in Participants With Hyperphosphatemia Receiving Maintenance Hemodialysis

This study is being conducted to characterize the safety, tolerability, and efficacy of AP306 at fixed doses in adults with hyperphosphatemia receiving mainten…

HyperphosphatemiaChronic Kidney Disease Requiring Chronic DialysisEnd Stage Renal Disease on Dialysis

Estimated

~$10 – $8,750

R1 TherapeuticsNCT06712654

A Prospective, Multicenter, Global Registry Evaluating Minimally Invasive Surgery for the Treatment of Acute Spontaneous Supratentorial Intracerebral Hemorrhage.

The goal of this observational study is to quantify the real-world effect of minimally invasive surgery (MIS) in patients with acute spontaneous supratentorial…

Intracerebral Hemorrhage

Estimated

~$10 – $750

Emory UniversityNCT07651631