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Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design
The study investigates the effects of alcohol consumption on social and individual behaviors using a within-subject design. Participants, aged 21-30, will atte…
Pregnenolone for the Treatment of Alcohol Use Disorder
This Phase 2 randomized cotrolled trial (RCT) will assess the safety and efficacy of pregnenolone (PREG; 300 mg/day, b.i.d dosing) vs. placebo (PBO) over a 12 …
A User-Customizable Personalized Normative Feedback Intervention for Alcohol Harm Reduction in Young Adults: Feasibility, Acceptability, and Preliminary Efficacy
The project will develop brief interventions that allow participants to customize which groups they receive feedback for in relation to things such as drinking…
Social Identity Mapping for Adolescent Recovery
The goal of this clinical trial is to address the gap between clinical treatment and adolescents' lived social environments by developing and testing a novel, …
Emergency Department Community Health Worker-Peer Recovery Navigation for Linkage to Recovery: A Mixed Methods Evaluation
This is an observational, prospective case-control study evaluating the effects of an emergency department community health worker-peer recovery specialist pro…
Advancing New Computer-based Health Outreach Regarding Sexual Behavior (ANCHORS) Study: UH3 Project
80 young adult men will complete an initial survey and receive 1 of 2 types of alcohol and sexual health education and information to encourage prevention of a…
Testing the Reward-Drinker Hypothesis of Naltrexone Using an Extended-Release Formulation
This study is a phase IV, two-arm, randomized, double-blind, placebo-controlled study to assess whether individuals identified as primarily reward drinkers are…
The Combination of Donepezil and Cognitive Training for Treating Alcohol Use Disorder
The goal of the project is to evaluate whether donepezil + cognitive remediation therapy is superior to placebo in reducing heavy drinking in patients with alc…
The Role of Brief Potent Glutamatergic Modulation in Addressing Problem Drinking: a Randomized, Controlled Trial
The proposed project tests the efficacy of glutamate modulators in non-depressed individuals with alcohol use disorder (AUD); the primary hypothesis is that th…
Behavioral and Functional Task Development, Implementation, and Testing
Background: \- Scientists know that alcohol use disorders affect brain structure. They want to know more about the effects of alcohol use disorders on a perso…
Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking
Using a randomized controlled trial (RCT), the goal of this study is to evaluate the ability of evidence based behavioral treatment (contingency management: CM…
Mobile Platform for Optimizing Wellness and Engagement in Recovery
This pilot study addresses the urgent public health crisis of co-occurring opioid and alcohol use disorders (OUD-AUD), leading causes of mortality in the Unite…