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Supplementation of Pomegranate Dietary Supplements and Characterization of Urolithin Metabotypes in Patients With Alcohol Use Disorder (AUD) and Alcohol-associated Liver Disease (ALD)
The goal of this project is to determine an individual's ability to generate active gut microbial metabolites called urolithins upon consumption of pomegranate…
Alcohol Use DisorderAlcohol-associated Liver DiseaseAlcoholic Cirrhosis+1 more
Estimated
~$10 – $750
University of LouisvilleNCT07678567
Phase 2
A Randomized, Double-Blind, Placebo-Controlled, Flexible Dose Phase 2 Study of Efficacy and Safety of Tirzepatide in Individuals With Alcohol Use Disorder and Metabolic Alcohol-associated Liver Disease
Background: People with alcohol use disorder (AUD) often develop metabolic alcohol-associated liver disease (MetALD). MetALD is a term for the heart, liver, o…
Metabolic Alcohol-associated Liver DiseaseAlcohol Use Disorder
Estimated
~$10 – $5,625
National Institute on Alcohol Abuse and Alcoholism (NIAAA)NCT07046819
Observational
Feasibility and Acceptability of a Novel Implementation Intervention to Promote Alcohol Use Disorder Treatment in Hepatology Clinics
The goal of this project is to improve provision of integrated medications for alcohol use disorder (MAUD) with brief counseling for patients with alcohol use …
Alcohol Use DisorderAlcohol-associated Liver Disease
Estimated
~$10 – $6,250
Yale UniversityNCT07525258
Phase 2
Lactobacillus Rhamnosus GG: A Novel Probiotic Therapy for Treating Alcohol Use Disorder
To test the efficacy of 6-month LGG compared to placebo in treating Alcoholic Use Disorder (AUD) and liver injury in Alcoholic Hepatitis (AH). And to evaluate …
Alcohol Use DisorderAlcohol-associated Liver Disease
Estimated
~$10 – $6,250
University of LouisvilleNCT05178069