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1,239 recruiting studies matching your filters

Epigenetic Mechanism Reprogramming Mucosal Anti-viral Immunity in Allergic Asthma VIRAL MUCOSAL REPROGRAMMING

This is a mechanistic, controlled, open-label, single-site study to evaluate the effects of RG-RV16 inoculation on airway mucosal gene expression and airway re…

AsthmaAllergic RhinitisCat Allergy+1 more

Estimated

~$10 – $6,250

The University of Texas Medical Branch, GalvestonNCT05331170

Sleep and Physical Activity in Patient and Caregiver Dyads Following Allogeneic Hematopoietic Cell Transplantation

To understand the changes in health-related quality of life of patients and caregivers after allogeneic hematopoietic cell transplantation.

Physical ActivitySleepAllogenic Hematopoietic Cell Transplant

Estimated

~$10 – $750

M.D. Anderson Cancer CenterNCT07140770

Phase 2

A Phase 2 Trial of Chemotherapy, Pembrolizumab, and Propranolol in Advanced Esophageal/Gastroesophageal Junction Adenocarcinoma Patients

This phase II trial tests what effects the addition of propranolol to pembrolizumab and standard chemotherapy (mFOLFOX) may have on response to treatment in pa…

Clinical Stage II Esophageal Adenocarcinoma AJCC v8Clinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+8 more

Estimated

~$10 – $7,500

Eosinophils and Inflammation, an Expanded Study

The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further charact…

Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory DiseaseFood Allergy

Estimated

~$10 – $675

Children's Hospital Medical Center, CincinnatiNCT00267501

WellSpan Study of Tracking Health and Resilience to Improve the Vitality of Individuals Experiencing Cancer [WellSpan-THRIVE]

Cancer affects millions of people worldwide and can significantly impact not only survival, but also day-to-day quality of life. Treatments such as surgery, ch…

Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or PalliativeCancer (Solid Tumors)Cancer (With or Without Metastasis)+3 more

Estimated

~$10 – $1,125

WellSpan HealthNCT07433660

Observational

Clinical Evaluation of Freeze-Dried Bone Allograft Compared to Collagen-Enriched Bovine Xenograft for Alveolar Ridge Preservation of Anterior Extraction Sockets.

The purpose of this study is to compare two different bone graft materials (freeze-dried bone allograft, FDBA and collagen-enriched bovine xenograft, CEBX) tha…

Ridge PreservationAllograftsExtraction, Tooth+1 more

Estimated

~$10 – $6,250

University of RochesterNCT06722482

Phase 2

Phase 2 Study of Ruxolitinib-Based Primary Treatment for Acute GVHD

This clinical trial will study ruxolitinib-based treatment of acute graft-versus-host-disease (GVHD) that developed following allogeneic hematopoietic cell tra…

Acute Graft-versus-host DiseaseAllogeneic Bone Marrow TransplantationAdverse Effects

Estimated

~$10 – $7,500

John LevineNCT06936566

Phase 1

A Phase Ib Trial of PBF-1129 and Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer

This phase I trial studies the side effects and best dose of PBF-1129 in combination with nivolumab in treating patients with non-small cell lung cancer that h…

Metastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage IV Lung Cancer AJCC v8+2 more

Estimated

~$10 – $7,500

Dwight OwenNCT05234307

Phase 1

A Phase I Dose Escalation Trial for Treatment of Chronic Thoracoabdominal Wall Pain Through Ablation of the Dorsal Spinal Nerve Using Single-Fraction Stereotactic Radiosurgery

The researchers are doing this study to find out whether stereotactic radiosurgery (SRS) is a safe, practical (feasible), and effective treatment for people wi…

Thoracoabdominal Wall PainSecondary to Parietal Pleura or Parietal Peritoneum Disease

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT05985148

Observational

Intervening on Frailty to Improve Outcomes for Older Allogeneic Transplant Recipients

This is an interventional pilot study to determine whether implementation of a supervised exercise program can improve outcomes in subjects undergoing allogene…

Allogeneic Transplantation

Estimated

~$10 – $6,250

Abramson Cancer Center at Penn MedicineNCT05612789

Phase 2

Phase II Open Label, Single-Arm Study of Cabozantinib in Combination With Pembrolizumab in the Treatment of Locally Advanced or Metastatic Adrenocortical Carcinoma

This phase II trial tests how well cabozantinib in combination with pembrolizumab works in treating patients with adrenocortical cancer that has spread to near…

Locally Advanced Adrenal Cortex CarcinomaAdrenal Cortical CarcinomaStage III Adrenal Cortex Carcinoma+2 more

Estimated

~$10 – $6,250

Emory UniversityNCT06006013

Development and Analysis of a Sample Bank (Blood, Urine, and Stool) for Cancer Patients, Enabling the Systematic Study of the Effect of Blood, Urinary Tract, and Gut Microbiomes on Response to Treatment

This study is aimed at understanding the impact of gut microbiota on efficacy of cancer therapies, in particular checkpoint inhibitors, and using the resulting…

Carcinoma, Non-Small-Cell LungCarcinoma, Colorectal

Estimated

~$10 – $1,050

Persephone BiosciencesNCT04291755