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1,241 recruiting studies matching your filters

Alpha/Beta T-cell and B-cell Depleted Allogeneic Transplantation (IDE 13641) Followed by Blinatumomab Therapy for High-Risk B-Acute Lymphoblastic Leukemia: A Pilot Study

This trial will assess the feasibility of alpha/beta T-cell and B-cell depleted allogeneic hematopoietic cell transplantation (HCT) followed by blinatumomab th…

B-cell Acute Lymphoblastic LeukemiaB-cell Childhood Acute Lymphoblastic LeukemiaB-Cell ALL, Childhood

Estimated

~$10 – $6,250

Medical College of WisconsinNCT04746209

Predictors of Health-Related Quality of Life in Adults With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

The study aims to improve our understanding of how quality of life, fatigue, and symptoms change over 2 years when participants are treated for chronic lymphoc…

Small Lymphocytic Lymphoma (SLL)Chronic Lymphocytic Leukemia (CLL)

Estimated

~$10 – $750

H. Lee Moffitt Cancer Center and Research InstituteNCT07030400

Phase 1

Trial of ctDNA of Guidance to Determine PostOperative Radiation Therapy (PORT) for Minimal Residual Disease (MRD) for Lung Cancer: the MRD-PORT Trial

Primary Objective: Evaluate the role of ctDNA positivity in decision making for postoperative therapy for non-small cell lung cancer. The plan for postoperati…

Lung CancerNon Small Cell Lung CancerLung Cancer Recurrent

Estimated

~$10 – $6,250

Rutgers, The State University of New JerseyNCT06979661

Phase 1

A Phase 1/2, First-in-Human Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of AVZO-021 as a Single Agent and in Combination Therapy in Patients With Advanced Solid Tumors

This study, the first clinical trial of AVZO-021, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and a…

Advanced Solid TumorHR+/HER2- Breast CancerHR+, HER2-, Advanced Breast Cancer+6 more

Estimated

~$10 – $8,750

Avenzo Therapeutics, Inc.NCT05867251

Observational

Supporting Practices In Respecting Elders Phase 2

This study consists of three aims focused on examining the feasibility of adding the Geriatric Resources and Assessment for the Care of Elders (GRACE) model to…

AgingPreventive CareMultimorbidity+1 more

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT07166861

Predicting Immunotherapy Efficacy from Analysis of Pre-treatment Tumor Biopsies

This study will collect de-identified tumor samples, with correlated clinical/demographic data and tissue histology, from patients selected or scheduled for pr…

Cancer of Head and NeckLung Cancer, Nonsmall CellSmall-cell Lung Cancer+8 more

Estimated

~$10 – $1,050

Cofactor Genomics, Inc.NCT04510129

Phase 2

Phase 2 Pragmatic Trial Investigating Sentinel Lymph Node Biopsy (SLNB) Efficacy and Safety in Patients With Clinically Node-Negative (cN0), High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck

This is a phase 2 pragmatic study at a single site that evaluates the clinical benefit of SLNB in patients with high-risk cSCC and cN0. The primary goal is to …

Cutaneous Squamous Cell Carcinoma of the Head and NeckClinically Node-Negative (cN0)High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck

Estimated

~$10 – $6,250

University of California, DavisNCT06990737

Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

Patients with resectable solid primary cancers and even limited number of metastases are potentially curable. However, most patients develop recurrences despit…

Non-small Cell Lung CancerEsophageal CancerGastric Cancer+3 more

Estimated

~$10 – $750

University of Missouri-ColumbiaNCT02838836

Long-term Follow-up of Subjects Treated With CAR T Cells

This is a single site, non-randomized, open-label, long-term safety and efficacy follow-up study for Phase 1 studies that evaluate the safety and efficacy of C…

Long Term Adverse EffectsCAR-TDuty to Follow Up+4 more

Estimated

~$10 – $1,125

Marcela V. Maus, M.D.,Ph.D.NCT05024175

Observational

Effectiveness of the SoundHeal (Heal) Multi-Sensory Integrative Therapy in Enhancing Emotional Regulation Among Justice-Involved Youth and Its Effect on Therapeutic Alliance and Mental Health Outcomes

Emotional dysregulation in justice-involved youth (JIY) is a condition that significantly impacts young people, their families, and juvenile justice and public…

Emotional DysregulationTherapeutic AllianceDepression Disorder+4 more

A Phase II, Multisite, Open-label Trial of Pumitamig (BNT327) in Combination With Standard-of-care Chemotherapy in First-line and Second-line Non-small Cell Lung Cancer (NSCLC)

This is a Phase II, multisite, open-label study consisting of two parts in participants with advanced/metastatic Non-small Cell Lung Cancer (NSCLC) which progr…

Non-small Cell Lung Cancer

Estimated

~$10 – $7,500

BioNTech SENCT06841055

Phase 1

Feasibility Trial of Pembrolizumab Plus Ultrasound-Induced Microbubble Cavitation in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

This is a feasibility trial studying anti-PD-1 therapy (Pembrolizumab) among patients with R/M HNSCC, delivered with ultrasound-induced microbubble cavitation,…

Head and Neck CancerHead and Neck Small Cell CarcinomaMetastatic Head and Neck Cancer+1 more

Estimated

~$10 – $6,250

Thomas Jefferson UniversityNCT07501650