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National Cancer Institute (NCI)NCT05828069

Phase 2

A Phase II Trial of the MEK Inhibitor Mirdametinib in Histiocytic Disorders

The purpose of this study is to see if treatment with mirdametinib in patients with Langerhans cell histiocytosis (LCH) or other histiocytic disorders will be …

Langerhans Cell Histiocytosis (LCH)Juvenile Xanthogranuloma (JXG)Rosai-Dorfman Disease (RDD)+1 more

Children's Hospital Medical Center, CincinnatiNCT06153173

Posttraumatic Stress DisorderAnger

A Randomized Controlled Trial of the Mobile Anger Reduction Intervention for Veterans

Difficulty controlling anger is the most commonly reported reintegration concern among combat Veterans, especially those with a diagnosis of posttraumatic stre…

VA Office of Research and DevelopmentNCT06094933

Asperger's DisorderAsperger DisorderAutism Disorder+41 more

QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (UPSTO App No(s). 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428) is Frontier AI/AGI Public Health Trials Sandbox Framework That Provides Free Public Health Services to Registered and Sponsored Visitors/Occupants for RDT&E Under 28 U.S.C. 1498 (Classified as a PPA, OTA Under 10 U.S. Code 4001, 4022), Serving as a Global Intranet of Humans Resident Patients Among Multiple Enclave Communicates ("AI Microcities" or "Smart Health Cities") Living and Learning With AI Robotics for Non-medicinal Treatment.

BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum AI/AGI Public Health Agency), known operationally as the …

Mild Traumatic Brain Injury (mTBI)Traumatic Brain InjuryAnger

Examining the Efficacy of the Man Therapy Platform in Reducing Problematic Anger Among Military Service Members With and Without a TBI History: A Randomized Controlled Trial

The goal of this randomized controlled trial is to determine if an interactive digital solution, Man Therapy, reduces indices of problematic anger in male mili…

University of Colorado, DenverNCT07604701

Post-traumatic Stress Disorder (PTSD)Trauma and Stress Related DisordersOccupational Stress+4 more

Grappling With Trauma: Evaluating Brazilian Jiu-Jitsu for Trauma Symptom Reduction Among First Responders

This study explores whether participating in an 8-week Brazilian Jiu-Jitsu (BJJ) program is linked to changes in trauma-related symptoms among first responders…

Sam Houston State UniversityNCT07783516

The Project: EveryChild Protocol: A Registry, Eligibility Screening, Biology and Outcome Study

This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patien…

Adrenal Gland PheochromocytomaCarcinoma In SituCentral Nervous System Neoplasm+15 more

Children's Oncology GroupNCT02402244

~$10 – $1,125

Irritable MoodTemper TantrumAnger

The Efficacy of Parent Management Training to Treat Irritability

The goal of this clinical trial is to see if 12 sessions of a Parent Management Training program can treat irritability in children aged 10-14 years old. The m…

University of Colorado, DenverNCT06020261

Trauma InjuryDepressionAnxiety+2 more

Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries

Animal assisted therapy (AAT) with dogs has been shown to be beneficial for a wide range of patients with both acute and chronic illnesses, including spinal co…

Boston Medical CenterNCT06812247

Histiocytic Disorder Follow-up Study

The purpose of the study is to describe the burden of chronic health conditions, psychological dysfunction, chronic pain, healthcare utilization, worse health-…

HistiocytosisLangerhans Cell HistiocytosisErdheim-Chester Disease+3 more

University of Alabama at BirminghamNCT05915208

~$10 – $750

TBISuicide PreventionVeterans+3 more

A Mixed Methods Pilot Trial of the STEP Home Workshop to Improve Reintegration and Reduce Suicide Risk for Recently Transitioned Veterans

Risk of Veteran suicide is elevated during the first year of transition from military service to civilian life. Most Veteran suicides occur among Veterans who …

VA Office of Research and DevelopmentNCT05995678

Phase 3

Randomization of Cytarabine Monotherapy Versus Standard-of-Care Vinblastine/Prednisone for Frontline Treatment of Langerhans Cell Histiocytosis (TXCH LCH0115)

Langerhans Cell Histiocytosis (LCH) is a type of cancer that can damage tissue or cause lesions to form in one or more places in the body. Langerhans cell hist…

Langerhans Cell Histiocytosis