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16 recruiting studies matching your filters
Phase 2
Targeted Approach to Langerhans Cell Histiocytosis (LCH) Using MEK Inhibitor, Trametinib
The purpose of this Phase II clinical trial is to establish the safety and effectiveness of trametinib, a targeted therapy, for the treatment of newly or recen…
Langerhans Cell Histiocytosis
Estimated
~$10 – $7,500
Cook Children's Health Care SystemNCT06582745
Phase 2
A Phase 2 Study to Assess the Safety and Efficacy of Cobimetinib in Refractory Langerhans Cell Histiocytosis, LCH-Associated Neurodegenerative Disease, and Other Histiocytic Disorders.
This is a research study of a drug called cobimetinib in children and adults diagnosed with Langerhans cell histiocytosis (LCH), and other histiocytic disorder…
Langerhan's Cell HistiocytosisJuvenile XanthogranulomaErdheim-Chester Disease+4 more
Estimated
~$10 – $7,500
Carl AllenNCT04079179
Observational
Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms
Art therapy is used across the Military Health System for treatment of posttraumatic symptoms, but there is limited research on how art therapy is able to rest…
PTSDMilitary ActivityPost-Traumatic Headache+12 more
Estimated
~$10 – $6,250
Walter Reed National Military Medical CenterNCT05414708
Observational
A Randomized Controlled Trial of the Mobile Anger Reduction Intervention for Veterans
Difficulty controlling anger is the most commonly reported reintegration concern among combat Veterans, especially those with a diagnosis of posttraumatic stre…
Posttraumatic Stress DisorderAnger
Estimated
~$10 – $5,625
VA Office of Research and DevelopmentNCT06094933