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7 recruiting studies matching your filters

Individualized Response Assessment to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Primaries

Background: Cytoreductive surgery (CRS) removes tumors in the abdomen. HIPEC is hyperthermic (heated) chemotherapy that washes the inside of the abdomen. CRS …

Peritoneal MesotheliomaPeritoneal CarcinomatosisOvarian Cancer+4 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT04847063

Phase 1

Liposomal Irinotecan (Nal-IRI) Plus 5-fluorouracil and Leucovorin (5-FU/LV) Plus Oxaliplatin (NALIRIFOX) as First-Line Chemotherapy for Patients With Advanced Small Intestine and Appendiceal Cancers

This study will evaluate the safety and efficacy of NALIRIFOX per NAPOLI-3 regimen as first-line chemotherapy for patients with advanced small intestine and ap…

Advanced Small Intestine CancerAppendiceal Cancers

Estimated

~$10 – $6,250

The Methodist Hospital Research InstituteNCT07060014

Observational

A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for High-Grade Appendiceal and Colorectal Adenocarcinoma With Peritoneal Metastasis

This study will evaluate the role of mass-based response testing (MRT) to select and deliver personalized hyperthermic intraperitoneal chemotherapy (HIPEC) reg…

Appendiceal CancerColorectal AdenocarcinomaPeritoneal Metastases

Estimated

~$10 – $6,250

Yale UniversityNCT07291180

Observational

Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG)

This is a phase 2 pragmatic study that evaluates the clinical benefit of continuing systemic therapy with the addition of locally ablative therapies for oligo-…

Small Bowel CancerColorectal CancerAppendiceal Cancer+5 more

Estimated

~$10 – $6,250

University of California, DavisNCT06101277

Molecular Profiling for Tumor Characterization and Risk Stratification in Patients With Appendiceal Cancer

This study investigates integrated epigenetic and epitranscriptomic features of appendiceal cancer using archived tumor tissue specimens from the same patient …

Appendiceal CancerAppendiceal Adenocarcinoma

Estimated

~$10 – $750

City of Hope Medical CenterNCT07587268

Genetics of Appendix Cancer: The GAP Study

The GAP Study is a prospective cohort study designed to comprehensively investigate genetic variations that may contribute to cancer development among individu…

Appendix CancerAppendiceal CancerAppendiceal Neoplasms+12 more

Estimated

~$10 – $1,125

Andreana Holowatyj, PhD, MSCINCT05734430

Phase 4

Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)

This is an open-label study in adults to determine feasibility of using CYTALUX™ (pafolacianine) injection with near-infrared (NIR) fluorescent imaging for det…

Gastrointestinal CancerGastric CancerEsophageal Cancer+1 more

Estimated

~$10 – $6,250

Cedars-Sinai Medical CenterNCT07124351