Clinical data regarding quality of life in patients with refractory ascites is limited and preceded the development of newer questionnaires that may be more ro…

Ascites HepaticAscites, Malignant

~Estimated

~$10 – $750

Abramson Cancer Center at Penn MedicineNCT05726747

Phase 2

Albumin Assisted Diuresis in Patients with Cirrhosis Decompensated by Ascites and Peripheral Edema, a Proof-of-concept Double Blind Randomized Trial

A small, pilot proof-of-concept placebo-controlled trial to explore the effects of albumin on diuresis in patients with cirrhosis, ascites and lower extremity …

CirrhosisAscites Hepatic

~Estimated

~$10 – $7,500

Anahita Rabiee MD MHSNCT06812390

Phase 1

A Phase 1 Open Label Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PHIN-214 in Adults With Child Pugh A and B Cirrhosis

This 2-part study will evaluate PHIN-214 given as a single one-time dose (Part 1) and in multiple doses (given as daily doses for 28-days) (in Part 2). Specifi…

Cirrhosis, LiverLiver FibrosisAscites Hepatic

~Estimated

~$10 – $8,750

PharmaINNCT05490888