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Phase 2
Pediatric Asthma Trial of Corticosteroid Heterogeneity (PATCH): A Phase 2 Prospective Randomized Open Blinded End-point (PROBE) Design, Randomized Clinical Trial of Dexamethasone Versus Methylprednisolone for Pediatric Critical Asthma
Acute asthma exacerbation is caused by dysregulated pulmonary inflammatory pathways such that standard treatment includes prompt administration of exogenous sy…
Asthma (Diagnosis)
Johns Hopkins All Children's HospitalNCT07455396
Body Composition Related Evaluation of Airway Tone and Hyper-rEactivity Using Oscillometry
This study will determine if airway resistance to airflow and pressure, measured by Oscillometry, is associated with abnormal findings on methacholine challeng…
BreathingLung Function DecreasedAsthma (Diagnosis)+1 more
University of RochesterNCT07356310
Phase 1
A Single-Center, Single-Arm, Phase 1b Study to Evaluate the Effects of ADO-5030 on a Bronchoconstriction Challenge
This is a Phase 1 study to learn about the safety and pharmacokinetics of the study drug in patients with asthma and whether the study drug has effect during a…
Asthma (Diagnosis)
AdovateNCT07281274
Observational
Optimizing a Sensor-Enabled mHealth Intervention for Adolescents With Suboptimal Asthma Control
Asthma affects nearly 1 in 10 teenagers in the United States and can seriously impact their health and daily life. Teens are expected to manage their asthma by…
Asthma (Diagnosis)
University of KansasNCT07301060