Find your next paid study

Memorial Sloan Kettering Cancer CenterNCT07223034

Phase 2

Phase 2 Study of Ribociclib-Containing Post-Radiotherapy Combinations in Pediatric and Young Adult Patients Newly Diagnosed With High-Grade Glioma, Including Diffuse Intrinsic Pontine Glioma: Ribociclib and Everolimus for HGG/DIPG Which Harbor Alterations of the Cell Cycle and/or PI3K/mTOR Pathways AND Ribociclib and Temozolomide for DHG, H3G34-mutant

The goal of this study is to determine the efficacy of the 1) ribociclib and everolimus to treat pediatric and young adult patients newly diagnosed with a high…

High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more

Nationwide Children's HospitalNCT05843253

Phase 2

A Biomarker-Guided Phase 2 Study of DB107-RRV (Retroviral Replicating Vector) Combined With DB107-Flucytosine Extended-Release Tablets in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

The purpose of this study is to determine if the investigational products, DB107-RRV and DB107-FC, as a combination treatment will shrink high-grade glioma (HG…

High Grade GliomaAnaplastic Astrocytoma

~$10 – $7,500

Ashish ShahNCT06264388

Glioblastoma MultiformeAnaplastic Astrocytoma

Phase I/II Trial Of Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab (Avastin) for Treatment of Relapsed/Refractory Glioblastoma Multiforme and Anaplastic Astrocytoma.

The high-grade malignant brain tumors, glioblastoma multiforme (GBM) and anaplastic astrocytoma (AA), comprise the majority of all primary brain tumors in adul…

Northwell HealthNCT01269853

~$10 – $7,500

Loupe-Based Intraoperative Fluorescence Imaging for the Guidance of Brain Tumor Surgery

Glioblastoma multiforme (GBM) and anaplastic astrocytoma (AA) are the most common primary malignant brain tumors. Survival of patients with these brain tumors …

Glioblastoma MultiformeAnaplastic Astrocytoma

~$10 – $1,125

Guoqiang YuNCT04780009

Glioblastoma MultiformeAnaplastic AstrocytomaGliosarcoma

A Phase I/II Study of Pembrolizumab and M032 (NSC 733972), a Genetically Engineered HSV-1 Expressing IL-12, in Patients With Recurrent/Progressive and Newly Diagnosed Glioblastoma Multiforme, Grade 3 or Grade 4 Astrocytoma, or Gliosarcoma

This Phase I (Cohort I and Cohort II) and Phase II trial is designed to confirm the safety and tolerability of Pembrolizumab when given in conjunction with M03…

University of Alabama at BirminghamNCT05084430

AstrocytomaGlioblastomaProgressive Disease

First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma

This is a single center, first-in cancer-type phase I clinical trial of FT536 for adult patients with recurrent WHO Grade 4 astrocytoma, irrespective of IDH-mu…

Masonic Cancer Center, University of MinnesotaNCT07560865

Central Nervous System NeoplasmsGlioblastomaGliosarcoma, Adult+20 more

A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

The primary objective of this Phase 1, open-label, dose-escalation, and exploratory study is to evaluate the safety and tolerability profile (establish the max…

GlioblastomaHigh-grade GliomaGlioblastoma, IDH-wildtype+9 more

~$10 – $8,750

Jazz Pharmaceuticals

The SUPRAMAX-study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)

A greater extent of resection of the contrast-enhancing (CE) tumor part has been associated with improved outcomes in high-grade glioma patients. Recent result…

Jasper GerritsenNCT06118723

~$10 – $1,125

Glioblastoma MultiformeAnaplastic AstrocytomaFibrillary Astrocytomas+5 more

Phase I/II Trial of Repeat Dosing of Super-Selective Intraarterial Infusion of Erbitux (Cetuximab) and Avastin (Bevacizumab) for Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age

This study assesses the safety and efficacy of repeat monthly dosing of super-selective intra-arterial cerebral infusion (SIACI) of cetuximab and bevacizumab i…

University of MiamiNCT05956821

Grade II GliomaGrade III GliomaGrade IV Glioma+5 more

A Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Primary Brain Tumors

This pilot study will assess the safety and feasibility of using an implantable microdevice to measure local intratumor response to chemotherapy and other clin…

~$10 – $7,500

Oliver JonasNCT04135807

Glioblastoma, IDH-wildtypeGlioblastomaGlioblastoma Multiforme+4 more

An Open-label, Phase 1b Study to Evaluate the Safety and Tolerability of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

The purpose of this study is to establish the recommended phase 2 dose of eflornithine in combination with temozolomide in patients whose glioblastoma or astro…