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Longitudinal Study for the Assessment of MRI Based Biomarkers as a Predictors of Clinical Endpoints in Pediatric Onset Autoimmune Liver Disease
Autoimmune liver diseases (AILD), which include Primary Sclerosing Cholangitis (PSC) and Autoimmune Hepatitis (AIH) are a common etiological factor for chronic…
Autoimmune Liver DiseaseAutoimmune HepatitisPrimary Sclerosing Cholangitis
Children's Hospital Medical Center, CincinnatiNCT03178630
Cross-sectional Study for Assessment of MRI Based Biomarkers of Bile Duct Injury and Hepatic Fibrosis in Pediatric Onset Autoimmune Liver Disease
Autoimmune liver diseases (AILD), which include Primary Sclerosing Cholangitis (PSC) and Autoimmune Hepatitis (AIH) are a common etiological factors for chroni…
Autoimmune Liver DiseasePrimary Sclerosing CholangitisAutoimmune Hepatitis
Children's Hospital Medical Center, CincinnatiNCT03175471
Phase 1
A 12-Month, Open-Label Study Evaluating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Siplizumab as Induction Therapy in Patients With Autoimmune Liver Diseases Undergoing Liver Transplantation (SET-SAIL)
There is a significant unmet need for safe and effective therapeutic approaches to prevent immune-mediated graft injury and its complications in liver transpla…
Autoimmune Liver DiseaseLiver Transplant DisorderAutoimmune Hepatitis+3 more
Elizabeth C. VernaNCT06455280