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NIAID Centralized Sequencing Protocol
Background: Genetic testing called "sequencing" helps researchers look at DNA. Genes are made of DNA and are the instructions for our bodies to function. We a…
AtopyPrimary ImmunodeficiencyAutoimmunity+1 more
National Institute of Allergy and Infectious Diseases (NIAID)NCT03206099
Mechanisms of Immunotoxicology in Cancer Patients
The purpose of this study is to better understand how the treatment of cancer with immune checkpoint inhibitors (ICI) leads to the development of autoimmunity.…
AutoimmunityCancerImmunotoxicity+1 more
Abramson Cancer Center at Penn MedicineNCT04119713
Phase 4
An Open-label, Multi-center Protocol for Patients Who Have Completed a Previous Novartis Sponsored Secukinumab Study and Are Judged by the Investigator to Benefit From Continued Secukinumab Treatment
The purpose of this study is to assess long term safety in participants who have completed a Novartis trial with secukinumab, have been judged by the investiga…
Autoimmunity, Inflammation
Novartis PharmaceuticalsNCT04638647