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Blinatumomab's Outcome On Serologic Titers and Efficacy of Revaccination
The goal of this observational study is to establish a clear vaccination protocol for pediatric patients (less than 21 years old) who have received treatment f…
B-Cell ALLB-Cell Acute Lymphoblastic LeukaemiaB-Cell Lymphoblastic Leukemia+5 more
Arkansas Children's Hospital Research InstituteNCT07422337
Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy (PROSPER)
This study is being done to learn more about the short-term and long-term side effects of CAR-T cell therapy. Specifically, researchers want to know how often …
B-ALLHematologic MalignancySolid Tumor
St. Jude Children's Research HospitalNCT06579469
Phase 1
Phase 1/2 Dose Escalation Study of CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies
Background: Acute lymphoblastic leukemia (ALL) is the most common cancer in children. About 90% of children and young adults who are treated for ALL can now b…
B-NHLB-Non Hodgkin LymphomaAcute Lymphocytic Leukemia+8 more
National Cancer Institute (NCI)NCT05442515