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CAR T-cell Long-Term Follow-Up, Quality of Life and Adverse Reactions
To learn more about the long-term health in patients treated for B-Cell Acute Lymphoblastic Leukemia (B-ALL) with Cluster of Differentiation antigen 19 (CD19) …
B-Cell Acute Lymphoblastic Leukemia (B-ALL)
St. Jude Children's Research HospitalNCT07048535
Phase 1
A Phase 1/2 Study to Evaluate the Safety and Efficacy of AZD0486 in Adolescent and Adult Participants With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukaemia
This is a Phase 1/2, global multicentre, open-label, single-arm, dose escalation and dose optimisation study of AZD0486 to evaluate the safety, tolerability, a…
B-cell Acute Lymphoblastic Leukemia (B-ALL)
AstraZenecaNCT06137118
Phase 1
A Modular Phase I/II, Open-label, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Preliminary Efficacy of AZD4512 Monotherapy or in Combination With Anticancer Agent(s) in Participants With Acute Lymphoblastic Leukemia
The study is intended to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of AZD4512 in patients with relapsed/refractory B-Ce…
B-cell Acute Lymphoblastic Leukemia (B-ALL)
AstraZenecaNCT07109219
Blinatumomab's Outcome On Serologic Titers and Efficacy of Revaccination
The goal of this observational study is to establish a clear vaccination protocol for pediatric patients (less than 21 years old) who have received treatment f…
B-Cell ALLB-Cell Acute Lymphoblastic LeukaemiaB-Cell Lymphoblastic Leukemia+5 more
Arkansas Children's Hospital Research InstituteNCT07422337