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28 recruiting studies matching your filters
Phase 1
Phase 1/Phase 2 Open Label Trial of a Novel Indenoisoquinolone C-MYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
Background: Glioblastoma is a common brain cancer in adults. Treatment includes surgery, radiation, and chemotherapy. But this cancer can return after treatme…
Recurrent GlioblastomaGlioblastoma IDH (Isocitrate Dehydrogenase) WildtypeRelapsed Cancer+12 more
National Institute of Neurological Disorders and Stroke (NINDS)NCT07416188
Phase 2
Characterization of 18F-Fluciclovine PET Amino Acid Radiotracer in Resected Brain Metastasis
This study is for patients who have had surgery to remove brain metastasis and are planned to have stereotactic radiosurgery (SRS) after their brain surgery. I…
Brain MetastasesBrain Cancer
Baptist Health South FloridaNCT05554302
Phase 2
Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker: Correlation With Preoperative MR, ALA-induced PpIX Fluorescence, and Histopathology
This clinical research will evaluate the diagnostic potential of fluorescein as visualized through an operating microscope relative to 1) contrast enhancement …
Brain Cancer
David W. RobertsNCT02691923
Phase 1
Phase I Study of Replication-Competent Adenovirus-Mediated Double Suicide Gene Therapy With Stereotactic Radiosurgery in Patients With Recurrent or Progressive High Grade Astrocytomas
The primary goal of this Phase I study is to determine the maximum tolerated dose of oncolytic adenovirus mediated double suicide-gene therapy in combination w…
Malignant Glioma of BrainAstrocytomaMalignant Astrocytoma+6 more
Henry Ford Health SystemNCT05686798