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The SUPRAMAX-study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)
A greater extent of resection of the contrast-enhancing (CE) tumor part has been associated with improved outcomes in high-grade glioma patients. Recent result…
GlioblastomaHigh-grade GliomaGlioblastoma, IDH-wildtype+9 more
Jasper GerritsenNCT06118723
Phase 3
A Phase 3, Open-label, Randomized 2-arm Study Comparing the Clinical Efficacy and Safety of Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma
The goal of this Phase 3 clinical trial is to compare the efficacy of niraparib versus temozolomide (TMZ) in adult participants with newly-diagnosed, MGMT unme…
GlioblastomaGBMBrain Neoplasms, Adult, Malignant+1 more
Ivy Brain Tumor CenterNCT06388733
The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma: Study Protocol for An International Multicenter Prospective Cohort Study (ENCRAM 2301)
Resection of glioblastoma in or near functional brain tissue is challenging because of the proximity of important structures to the tumor site. To pursue maxim…
Glioblastoma, IDH-wildtypeGlioblastomaGlioblastoma Multiforme of Brain+6 more
Erasmus Medical CenterNCT06273176