Browse Studies — Arctuva

Phase 1

A Phase 1/1b Study of Autologous b7-h3 Chimeric Antigen Receptor t Cells (b7-h3.cd28z.Cart) in Children and Young Adults With Recurrent or Progressive Cns Neoplasms Expressing b7-h3 Target

The purpose of this research study is to test the safety and effectiveness of a cell therapy at different doses for children and young adults with recurrent or…

Central Nervous System NeoplasmsBrain TumorBrain Tumor, Recurrent+11 more

Estimated

~$10 – $7,500

Robbie MajznerNCT07390539

A Multicenter Observational Study of GammaTile™ Surgically Targeted Radiation Therapy (STaRT) in Intracranial Brain Neoplasms

The objectives of this registry study are to evaluate real-world clinical outcomes and patient reported outcomes that measure the effectiveness and safety of S…

Brain Tumor, RecurrentBrain TumorBrain Tumor, Primary+3 more

Estimated

~$10 – $1,050

GT Medical Technologies, Inc.NCT04427384

Phase 1

Chronic Convection Enhanced Delivery of Topotecan for Recurrent Malignant Glioma

The primary goal of this study is to establish the safety of chronic Convection Enhanced Delivery (CED) of the chemotherapeutic drug Topotecan for patients wit…

Brain Tumor, RecurrentMalignant Glioma (WHO Grade III or IV)IDH1/IDH2 Mutation

Estimated

~$10 – $7,500

Jeffrey N. BruceNCT06666712

Phase 2

Phase II Trial of Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory Glioblastoma Multiforme, Anaplastic Astrocytoma, and Anaplastic Oligoastrocytoma

Primary brain tumors are typically treated by surgery, radiation therapy and chemotherapy, either individually or in combination. Present therapies are inadequ…

GlioblastomaAnaplastic AstrocytomaAnaplastic Oligoastrocytoma+6 more

Estimated

~$10 – $7,500

Northwell HealthNCT02800486