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4 recruiting studies matching your filters
Phase 2
A Phase 2 Pivotal Study of BCB-276, a B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma
This study will evaluate BCB-276, an investigational B7-H3-targeted Chimeric Antigen Receptor (CAR) T cell therapy, in children and young adults with diffuse i…
Diffuse Intrinsic Pontine GliomaDIPGBrain Tumor+9 more
Estimated
~$10 – $8,750
BrainChild Bio, IncNCT07680439
Phase 1
Phase I/II Trial of Repeat Dosing of Super-Selective Intraarterial Infusion of Erbitux (Cetuximab) and Avastin (Bevacizumab) for Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age
This study assesses the safety and efficacy of repeat monthly dosing of super-selective intra-arterial cerebral infusion (SIACI) of cetuximab and bevacizumab i…
Glioblastoma MultiformeAnaplastic AstrocytomaFibrillary Astrocytomas+5 more
Estimated
~$10 – $6,250
University of MiamiNCT05956821
Phase 1
Adopting a Functional Precision Medicine Approach For Individualized Pediatric Cancer Treatments
Functional precision medicine (FPM) is a relatively new approach to cancer therapy based on direct exposure of patient- isolated tumor cells to clinically appr…
Recurrent Childhood Acute Myeloid LeukemiaRecurrent Childhood Acute Lymphoblastic LeukemiaRecurrent Childhood Large Cell Lymphoma+15 more
Estimated
~$10 – $6,250
Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
The purpose of this study is to prospectively collect specimens from pediatric patients with diffuse intrinsic pontine glioma or brainstem glioma, either durin…
Diffuse Intrinsic Pontine GliomaBrainstem Glioma
Estimated
~$10 – $675
Children's National Research InstituteNCT01106794