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1,058 recruiting studies matching your filters

Signature Development and Validation Protocol for an Epigenetic Assay in Diagnosing Breast Cancer

The purpose of this research study is to test a new process for diagnosing breast cancer by examining changes to your DNA that can be detected from a blood tes…

Breast Cancer (Locally Advanced or Metastatic)Healthy Volunteers (HV)Unhealthy Volunteers+1 more

Estimated

~$10 – $750

University of Maryland, BaltimoreNCT07374796

A Multi-center, Single Arm, Prospective Exploratory in Vitro Diagnostic Devices Clinical Performance Study to Evaluate of in Vitro Diagnostic Devices for Auxiliary Diagnosis That Classifies High-risk and Low Risk Patients With Breast Cancer by Analyzing Surface-enhanced Raman Spectroscopy (SERS) Profiles of Extracellular Vesicles (EVs) Extracted From Human Plasma Using Artificial Intelligence

EXoPERT has developed a liquid biopsy-based in vitro diagnostic medical device that can diagnose cancer through blood. The in vitro diagnostic medical device f…

A Phase 1, Open-Label, Dose-Escalation and Expansion Study of AGX101, a TM4SF1 Directed Antibody Drug Conjugate in Patients With Unresectable, Locally Advanced, or Metastatic Solid Tumors

AGX101 is an antibody-drug conjugate (ADC) therapy for tumor-forming cancers. The purpose of this study is to learn about AGX101 effects and safety at various …

CancerAdvanced CancerLocally Advanced Carcinoma+8 more

Estimated

~$10 – $8,750

Angiex, Inc.NCT06440005

Observational

Novel Cavity Marking Technique in Breast Cancer Patients Undergoing Breast Conservation Surgery With Oncoplastic Reconstruction for the Delivery of Adjuvant Radiotherapy and Accuracy of Recommended Re-excisions

This study will investigate a novel approach to marking surgical cavity margins following tumor resection, to allow for more accurate radiotherapy following on…

Ductal Carcinoma in SituBreast Cancer

Estimated

~$10 – $6,250

University of FloridaNCT06903468

Observational

Mind-Body Group Interventions for Psychological Distress in Young Breast Cancer Survivors

This is a two-arm randomized controlled trial (RCT) to determine the feasibility of a larger, fully powered trial in younger ER+ BCS undergoing endocrine thera…

Breast Cancer

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT07501637

Phase 2

A Double-blind, Phase II Randomized Study of Brain-directed Stereotactic Radiation With or Without AGuIX Gadolinium-based Nanoparticles in the Management of Brain Metastases at Higher Risk of Local Recurrence With Radiation Alone

The purpose of this study is to determine whether AGuIX (Activation and Guidance of Irradiation by X-ray) gadolinium-based nanoparticles make radiation work mo…

Brain CancerBrain MetastasesMelanoma+13 more

Estimated

~$10 – $6,250

Brigham and Women's HospitalNCT04899908

Observational

From Screening to Action: Implementing Navigation Interventions for Patients With Breast Cancer and High-risk Social Determinants of Health

This study aims to assess how individual patient social stressors are associated with barriers to care by analyzing a patient navigator system. Patient navigat…

Breast CancerCancer of Breast

Estimated

~$10 – $6,250

Washington University School of MedicineNCT07781800

Phase 2

A Pilot Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer

Breast cancer is estimated to affect approximately 300,000 women in the US in 2023. Studies demonstrate that 1 in 5 will develop breast cancer related lymphede…

Breast Cancer

Estimated

~$10 – $6,250

University of FloridaNCT06327490

Phase 1

Phase 1 Single-arm, Open-label, Multicenter Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in 2 Parallel Cohorts of Premenopausal Women With Early-stage and Advanced Hormone Receptor-positive (HR+) Breast Cancer

The primary objective of this trial is to evaluate ovarian suppression following treatment with ZOLADEX 10.8 mg by luteinizing hormone (LH) within each cohort.

Advanced Breast CancerEarly Breast Cancer

Estimated

~$10 – $8,750

TerSera Therapeutics LLCNCT07310420

Phase 2

"A Phase 2, Double Blinded, Randomized Controlled Trial of Evexomostat (SDX-7320) or Placebo in Combination With Eribulin for Patients With Metastatic Triple-Negative Breast Cancer and Metabolic Dysfunction: The ARETHA Study

The researchers are doing this study to find out whether the study drug, SDX-7320, when combined with the standard chemotherapy eribulin, is an effective treat…

Breast CancerMetastatic Triple-Negative Breast Cancer

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT05570253

Phase 1

An Open-label Multicenter Phase 1b-2 Study of Elacestrant in Combination With Abemaciclib in Women and Men With Brain Metastasis From Estrogen Receptor Positive, HER-2 Negative Breast Cancer

This is a multi-site, global, open-label study that includes a phase 1b evaluation of elacestrant in combination with abemaciclib in women and men with brain m…

Breast NeoplasmsBrain NeoplasmsNeoplasms by Site+5 more

Estimated

~$10 – $8,750

Stemline Therapeutics, Inc.NCT05386108

Phase 3

A Randomized, Open-label, Phase 3 Study of Adjuvant Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy

The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is ef…

Triple Negative Breast Cancer

Estimated

~$10 – $7,500

Gilead SciencesNCT05633654