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1,058 recruiting studies matching your filters

A Randomized Controlled Trial to Determine the Efficacy of Local Antibiotic Delivery in the Prevention of Breast Tissue Expander-Associated Infections

The researchers are doing this study to find out whether Stimulan Rapid Cure works to reduce the risk of infections in people getting tissue expanders placed d…

Breast Cancer

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT07220967

Observational

Breast Reconstruction Decision Aid (RECONJOINT)

The purpose of this study is to find out whether it is practical (feasible) to do a larger study looking at the effectiveness of the Breast Reconstruction Deci…

Breast Cancer

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT07335354

Phase 2

Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial

1\. Efficacy of PULSAR preoperative radiation 2. Evaluate potential of microbubble CEUS as an alternative to operative SLNBx 3. Evaluate potential of OA to eva…

Breast Cancer

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT06444269

QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

This study will assess whether a quantitative, HER2 assay can accurately and reliably discriminate between responders and non-responders among patients with HE…

HER2-positive Metastatic Breast Cancer

Estimated

~$10 – $750

Abramson Cancer Center at Penn MedicineNCT06551116

Observational

Locally ablatiVe therApy in oLigO-pRogressive sOlid tUmorS (VALOROUS)

This is a phase 2 pragmatic study that evaluates the clinical benefit of continuing systemic therapy with the addition of locally ablative therapies for oligo-…

Breast CancerOligoprogressiveHead and Neck Cancer+2 more

Estimated

~$10 – $6,250

University of California, DavisNCT06103669

Phase 1

Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Reconstruction

The purpose of the study is to determine whether pharmacologic delay using minoxidil in patients undergoing bilateral risk reducing mastectomy with reconstruct…

Breast ReconstructionPerfusion; ComplicationsHigh Risk for Breast Cancer+1 more

Estimated

~$10 – $6,250

Duke UniversityNCT07264790

Phase 1

First-in-Human Study of STX-478, a Mutant-Selective PI3Kα Inhibitor as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

Study STX-478-101 (LY4064809) is a multipart, open-label, phase 1/2 study evaluating the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor…

Breast CancerSolid Tumors, Adult

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT05768139

Phase 2

Phase IIA Trial of Acolbifene (20 mg) vs Low Dose Tamoxifen (5 mg) in Pre-menopausal Women at High Risk for Development of Breast Cancer

This phase IIA trial compares the effect of acolbifene versus low dose tamoxifen in preventing breast cancer in premenopausal women at high risk for developing…

Breast Atypical HyperplasiaBreast CarcinomaBreast Ductal Carcinoma In Situ+1 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT05941520

Phase 4

Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)

This is a post-marketing single arm, phase IV trial in which patients with high-risk early-stage HR+HER2- breast cancer will receive adjuvant abemaciclib in co…

Breast Cancer

Estimated

~$10 – $6,250

University of Illinois at ChicagoNCT06169371

Phase 1

Phase I/II Study of Naxitamab and Sacituzumab Govitecan in Patients With Metastatic Triple-negative Breast Cancer (TNBC)

This phase I/II trial tests the safety, best dose, and effectiveness of naxitamab in combination with sacituzumab govitecan in treating patients with triple-ne…

Metastatic Triple-Negative Breast Cancer

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT07011654

Observational

Adaptation and Implementation of an Evidence-Based Patient Navigation Intervention for Adolescent and Young Adult Cancer Survivors

The investigators propose to: 1) Adapt an evidence-based cancer-focused patient navigation (PN) program for the Adolescent and Young Adult (AYA) cancer survivo…

Breast CancerOvarian CancerCervical Cancer+6 more

Estimated

~$10 – $7,500

Kaiser PermanenteNCT07406087

Phase 1

A Phase 1 Study of Sigvotatug Vedotin in Advanced Solid Tumors

This trial will look at a drug called sigvotatug vedotin (SGN-B6A) alone and with pembrolizumab, with or without chemotherapy, to find out whether it is safe f…

Carcinoma, Non-Small Cell LungSquamous Cell Carcinoma of Head and NeckHER2 Negative Breast Neoplasms+9 more

Estimated

~$10 – $8,750

Seagen, a wholly owned subsidiary of PfizerNCT04389632