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4 recruiting studies matching your filters
Observational
Partial Breast Re-irradiation Using Ultra Hypofractionation: Phase 2 Multi-institutional Study (PRESERVE)
Breast-conserving surgery followed by re-irradiation with partial breast irradiation (rPBI) has recently been found to be a safe alternative to mastectomy for …
Breast CancerBreast Cancer Recurrent
Estimated
~$10 – $6,250
University Health Network, TorontoNCT05592938
Phase 1
REPEAT: RE-irradiation With a Partial brEast, Accelerated Technique: A Single-Center, Multi-site, Prospective, Phase I/II Clinical Trial
This study is to determine whether acute treatment-associated adverse events following breast re-irradiation with aPBI are acceptably low and to assess local c…
Breast Cancer Recurrent
Estimated
~$10 – $6,250
Dartmouth-Hitchcock Medical CenterNCT07612254
Phase 1
A Phase 1/2, Open-Label, Dose-Escalation and Expansion First-In-Human Study of ATX-295, an Oral Inhibitor of the Kinesin Motor Protein KIF18A, in Patients With Locally Advanced or Metastatic Solid Tumors, Including High-Grade Serous Ovarian Cancer
The goal of this study is to identify a safe and tolerated dose of the orally administered KIF18A inhibitor ATX-295. In addition, this study will evaluate the …
Advanced Solid TumorsBreast Cancer RecurrentOvarian Cancer+2 more
Estimated
~$10 – $8,750
Accent TherapeuticsNCT06799065
Phase 2
Towards Functional Precision Oncology to Predict, Prevent, and Treat Early Metastatic Recurrence of Triple Negative Breast Cancer
This is a prospective phase 2 study to use Functional Precision Oncology (FPO) to predict, prevent and treat early metastatic recurrence in subjects with HR-lo…
Breast Cancer Recurrent
Estimated
~$10 – $6,250
University of UtahNCT05464082