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Early Feasibility Study (EFS) to Assess the Safety and Performance of the Innoventric Trillium™ Stent Graft in the Treatment of Severe or Greater Tricuspid Regurgitation (TR)

Early Feasibility Study to evaluate the safety and performance of the Innoventric Trillium™ Stent Graft in the treatment of severe or greater tricuspid regurgi…

Tricuspid RegurgitationTricuspid Regurgitation Functional

Estimated

~$10 – $8,750

Innoventric LTDNCT06212193

Phase 1

A Phase 1a/1b, Multicenter, Open-label, Dose Escalation/Expansion, Multiple-dose Study to Evaluate the Safety and Activity of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

A phase 1a/1b, multicenter, open-label, dose escalation/expansion, multiple-dose study to evaluate the safety and activity of DR-0202 in patients with locally …

Triple Negative Breast CancerHER2-negative Breast CancerNon Small Cell Lung Cancer+9 more

The Effects of Resveratrol Supplementation on Functional and Systemic Markers of Muscle Damage and Cardiovascular Function in Response to a Damaging Isoinertial Squat Protocol

To examine the effects of once daily supplementation with 500mg VeriSperse® resveratrol (VRES) for 17 days on muscle function, delayed onset muscle soreness, s…

Effect of Resveratrol on Performance and Recovery

Estimated

~$10 – $6,250

University of Central FloridaNCT06723119

Phase 1

An Umbrella Phase 1b, Open-label, Multi-Cohort Study to Evaluate Safety, Pharmacokinetics, and Antiviral Activity of Novel Antiretrovirals in Participants With HIV-1 Substudy-05: GS-3242

This study is part of a master study. The goal of master protocol (GS-US-544-5905, NCT05585307) is to learn how novel antiretrovirals (medicines that stop the …

HIV-1-infection

Estimated

~$10 – $7,500

Gilead SciencesNCT07001319

Observational

Readiness Outcomes Affecting Return to Sport 3.0

The primary aim is to determine if MST will improve coping skills in young athletes returning to sport after ACLR as measured by ACSI-28. Participants will und…

ACL Reconstruction

Estimated

~$10 – $6,250

Boston Children's HospitalNCT07476430

Phase 3

Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children

The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory f…

Respiratory Syncytial Virus Infections

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT05026749

Observational

Preliminary Evaluation of a Remotely Controlled Mandibular Positioner to Predict Failure of Maxillomandibular Advancement Surgery for Obstructive Sleep Apnea

Maxillomandibular advancement (MMA) surgery, one of the most successful surgical procedures for the treatment of obstructive sleep apnea (OSA), is predominantl…

Obstructive Sleep ApneaMaxillomandibular Advancement Surgery

Estimated

~$10 – $6,250

University of MichiganNCT03929549

Observational

A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

A prospective, multicenter, single-arm study to evaluate the safety and effectiveness of the eCoin® implanted tibial nerve stimulator in subjects with urgency …

Overactive BladderUrge IncontinenceIncontinence, Urinary+1 more

Estimated

~$10 – $5,625

Valencia Technologies CorporationNCT05685433

Phase 4

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

To prospectively evaluate the efficacy and safety of DPYD-guided dosing strategies in a real-world clinical setting, specifically by comparing the incidence of…

Colorectal NeoplasmsBreast NeoplasmsHead and Neck Neoplasms+1 more

Estimated

~$10 – $6,250

Rutgers, The State University of New JerseyNCT07158164

Phase 2

Omalizumab Before Onset of Exacerbations

OBOE is a prospective, pilot, parallel group RCT with the overall aim of examining the effect of a single dose of anti-IgE (omalizumab) vs. placebo administere…

Asthma in ChildrenAtopyViral Upper Respiratory Infection

Estimated

~$10 – $5,625

Children's National Research InstituteNCT05332067

Phase 1

Phase I Trial of CA-4948 in Combination With FOLFOX/PD-1 Inhibitor +/- Trastuzumab for Untreated Unresectable Gastric and Esophageal Cancer

This is a phase I trial of CA-4948 in combination with FOLFOX/PD-1 inhibitor with or without trastuzumab for unresectable gastric, GEJ, and esophageal cancer. …

Gastric CancerEsophageal CancerStomach Cancer+2 more

Estimated

~$10 – $6,250

Washington University School of MedicineNCT05187182

Phase 2

Dissolved Phase Hyperpolarized Xenon-129 MRI: a Novel Biomarker to Quantify Pulmonary Pathology in Healthy Participants and E-cigarette Users

A two-center, longitudinal assessment of 40 electronic cigarette users and 40 healthy controls at the initial visit and a follow-up visit 12 months later. This…

Electronic Cigarette Related Lung Damage

Estimated

~$10 – $7,500

Y. Michael Shim, MDNCT06856525