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4,350 recruiting studies matching your filters

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder - OBOE-Mayo

The goal of this clinical trial is to identify the specific characteristics (phenotypes) that may be useful to help select the right medication for weight loss…

Bipolar I DisorderBipolar II DisorderSchizo Affective Disorder+3 more

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Mayo ClinicNCT07213466

Phase 2

Effect of PDE5 Inhibitor on Respiratory Symptoms in COPD Complicated by Pulmonary Hypertension

The investigators will study whether the drug tadalafil improves shortness of breath in 126 Veterans with Chronic Obstructive Pulmonary Disease (COPD) and high…

Chronic Obstructive Pulmonary DiseasePulmonary HypertensionDyspnea

Estimated

~$75 – $1,800

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT05937854

Phase 2

An Open-label, Long-term Study Evaluating RAP-219 in Adult Participants With Refractory Onset Seizures

This is a clinical research study for an investigational drug called RAP-219 in patients with Refractory Focal Epilepsy. This study is being conducted to deter…

Focal EpilepsyEpilepsyRefractory Focal Epilepsy+3 more

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Rapport Therapeutics Inc.NCT07219407

Observational

Enduring Migraine Benefit From Responsive Artery Coil Embolization (EMBRACE): A Single-Site, Non-Significant Risk Pilot Study of Middle Meningeal Artery Embolization Using FDA-Cleared Coils for Refractory Episodic Migraine

This single-site, open-label pilot study evaluates the safety, feasibility, and potential durability of the TEMMA procedure (Targeted Embolization for Migraine…

Migraine DisordersRefractory MigraineChronic Migraine

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Cortex NeurovascularNCT07313800

Observational

Clinical and Neurocomputational Effects of Behavioral Activation in Veterans With Impaired Social Functioning

Poor psychosocial functioning, including social disconnection, is common and disabling among Veterans, and often fails to improve following the best available …

Social AnhedoniaSocial Function Impairment

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT07697001

Observational

Evolution of the Chicago Classification: Bridging Physiology and Mechanics

Swallowing difficulties are extremely common and result in substantial morbidity, reduction in the quality of life, and mortality related to malnutrition and c…

DysphagiaAchalasia, EsophagealIneffective Esophageal Motility

Estimated

~$10 – $750

Actual pay is set by the research site.

Northwestern UniversityNCT06883175

Phase 1

Phase 1b/2a Study of RiMO-301 and Hypofractionated Radiotherapy With A PD-1 Inhibitor for the Treatment of Unresectable, Recurrent or Metastatic Head-Neck Cancer

This is a prospective, open-label, single arm, non-randomized study of RiMO-301 with hypofractionated radiation and a PD-1 Inhibitor in patients with unresecta…

Head Neck CancerIntratumoral Injection

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Coordination Pharmaceuticals, Inc.NCT05838729

Phase 1

Phase 1b/2 Study of Axatilimab (SNDX-6352) + Azacitidine (AZA) in Advanced Phase MPN, MPN/MDS Overlap or High-Risk CMML

This phase Ib/II trial tests the best dose of axatilimab and effectiveness of axatilimab with or without azacitidine for the treatment of patients with advance…

Atypical Chronic Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyelodysplastic/Myeloproliferative Neoplasm+5 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Uma BorateNCT06523556

Phase 2

Phase 2 Study of Ruxolitinib-Based Primary Treatment for Acute GVHD

This clinical trial will study ruxolitinib-based treatment of acute graft-versus-host-disease (GVHD) that developed following allogeneic hematopoietic cell tra…

Acute Graft-versus-host DiseaseAllogeneic Bone Marrow TransplantationAdverse Effects

Estimated

~$75 – $3,000

Actual pay is set by the research site.

John LevineNCT06936566

A Natural History Study of Children and Adults With Olfactory Neuroblastoma

Background: Olfactory neuroblastoma (ONB) is a rare cancer. It grows from tissue in the upper part of the nose cavity, related to the sense of smell and can a…

Olfactory NeuroblastomaEsthesioneuroblastoma

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT04755205

Observational

Test-to-PrEP: A Randomized Hybrid Implementation/Effectiveness Trial of a Social Network Strategy to Increase Equitable Reach of HIV Testing and PrEP Information

To compare the effectiveness of two social network strategies (direct distribution and referral-based distribution) in increasing HIV self-testing (HIVST) comp…

HIV Infections

Estimated

~$10 – $750

Actual pay is set by the research site.

University of MiamiNCT06927856

Observational

Home Hospital for Suddenly Ill Adults: A Clinical Trial

The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model ha…

InfectionHeart FailureCOPD+6 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Brigham and Women's HospitalNCT03524222