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4,613 recruiting studies matching your filters

A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Lumateperone in the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients 5 to 17 Years of Age

This is a multicenter, randomized, double-blind, placebo-controlled study in pediatric patients aged 5 to 17 years with a primary diagnosis of irritability ass…

Irritability Associated With Autism Spectrum Disorder

Estimated

~$10 – $8,750

Intra-Cellular Therapies, Inc.NCT06706674

Phase 1

A Phase I/II Open-label Dose Escalation and Dose Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of AZD5863, a T Cell-engaging Bispecific Antibody That Targets Claudin 18.2 (CLDN18.2) and CD3 in Adult Participants With Advanced or Metastatic Solid Tumors

This research is designed to determine if experimental treatment with AZD5863, a T cell-engaging bispecific antibody that targets Claudin 18.2 (CLDN18.2) and C…

Gastric CancerGastro-esophageal Junction CancerPancreatic Ductal Adenocarcinoma+1 more

Estimated

~$10 – $7,500

AstraZenecaNCT06005493

Phase 4

Anomalous Motor System Physiology in Attention Deficit Hyperactivity Disorder: Biomarker Validation and Modeling Domains of Function

Attention-Deficit/Hyperactivity Disorder (ADHD) is the most commonly diagnosed neurobehavioral disorder in childhood. Children with ADHD struggle in school due…

Attention Deficit Hyperactivity Disorder Combined

Estimated

~$10 – $7,500

Donald Gilbert, MD, MS, FAAN, FAAPNCT04421248

Observational

SAFEGUARD Level Up Study

This project will evaluate the effectiveness of Level Up: Boost Your Life Skills ("Level Up"), a strengths based, military-specific life skills training progra…

Risk Reduction BehaviorSuicide PreventionRisky Behavior+3 more

Estimated

~$10 – $6,250

Uniformed Services University of the Health SciencesNCT07286955

Phase 3

A Phase 3, Prospective, Multicenter, Double-Blind, Randomized, Controlled, Adaptive Study To Demonstrate The Safety And Efficacy Of DEFENCATH® In Reducing Central Line-Associated Bloodstream Infections (CLABSIs) In Adult And Adolescent Participants Receiving Total Parenteral Nutrition (TPN) Via Central Venous Catheter (CVC)

This is a Phase 3, randomized, double-blind, controlled, adaptive, 2-arm, multicenter study to demonstrate the efficacy and safety of DefenCath in adult and ad…

Central Line Associated Blood Stream Infections (CLABSI)

Estimated

~$10 – $8,750

CorMedix TherapeuticsNCT06822426

Phase 2

A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study of SUN-627 to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Impact on Measures of Neuroinflammation in the Central Nervous System in Participants With Non-Active Progressive Multiple Sclerosis (SPMS/PPMS)

The goal of this Phase 2 clinical trial is to investigate the safety and tolerability of SUN-627 in men and women aged 18-70 years old with a diagnosis of non-…

Primary Progressive Multiple SclerosisPrimary Progressive MSPrimary Progressive Multiple Sclerosis (PPMS)+6 more

Estimated

~$10 – $8,750

Sundance Biosciences, Inc.

Phase 4

COMBAT-SAB: Combination Antibiotic Therapy for Staphylococcus Aureus Bacteremia

The purpose of this study is to see if, in selected patients with a serious bacterial infection of the bloodstream, treating the bacterial infection with a com…

Staphylococcus Aureus Bacteremia

Estimated

~$10 – $8,750

Intermountain Health Care, Inc.NCT07376889

Phase 1

A Phase 1b/2, Open-Label Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

The purpose of this study is to assess the anti-tumor activity of amivantamab as a monotherapy (Cohorts A, B, and C), to assess the recommended phase 2 combina…

Advanced or Metastatic Colorectal Cancer

Estimated

~$10 – $8,750

Janssen Research & Development, LLCNCT05379595

Observational

Evaluating Care Integration Between Pediatric Primary Care Providers and WIC Nutritionists for Early Obesity Prevention Among WIC Mothers and Children

This study looks at whether using secure digital systems to share information between pediatric health care providers (during regular well-child visits) and so…

Weight Gain TrajectoryBMIResponsive Parenting+2 more

Estimated

~$10 – $6,250

Penn State UniversityNCT07494097

Phase 3

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study of the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants 40 to 80 Years of Age With Moderate to Very Severe COPD (PERSIST COPD-2)

The study primarily aims to demonstrate the superiority of GSK5784283 as an add-on therapy compared to placebo in reducing the annualized rate of moderate and …

Pulmonary Disease, Chronic Obstructive

Estimated

~$10 – $7,500

GlaxoSmithKlineNCT07780656

Phase 3

AN INTERVENTIONAL EFFICACY AND SAFETY, PHASE 3, DOUBLE-BLIND, 2-ARM STUDY TO INVESTIGATE ORALLY ADMINISTERED IBUZATRELVIR COMPARED WITH PLACEBO IN NON-HOSPITALIZED SYMPTOMATIC ADULT AND ADOLESCENT PARTICIPANTS WITH COVID-19 WHO ARE AT HIGH RISK OF PROGRESSING TO SEVERE ILLNESS

The purpose of the study is to evaluate whether ibuzatrelvir is effective and safe in adults and adolescents with COVID-19 who do not need to be in the hospita…

COVID-19 SARS-CoV-2 Infection

A Multicenter, Open-label, Interventional Phase I Trial to Determine the Dose and Evaluate the Pharmacokinetics (PK) and Safety of Lutetium Lu 177 Edotreotide Targeted Radiopharmaceutical Therapy (RPT) as Monotherapy or Following Standard of Care (SoC) for the Treatment of Somatostatin Receptor-positive Tumors in the Pediatric Population (KinLET).

The purpose of the study is to determine the appropriate pediatric dosage and evaluate the pharmacokinetics (PK) and safety of Lutetium Lu 177 Edotreotide Targ…

Somatostatin Receptor PositiveNETsLymphoma+5 more

Estimated

~$10 – $8,750

ITM Solucin GmbHNCT06441331