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4,469 recruiting studies matching your filters

A Phase 1 Multicenter, Open-Label, Dose-Escalation and Expansion Study of NTB-928, a FRα-Targeting Bispecific T Cell Engager, in Subjects With Relapsed/Refractory Ovarian Carcinoma

The goal of this clinical trial is to determine if NTB-928 can be given safely to adult females with ovarian cancer that has come back (relapsed) or stopped re…

Relapsed/Refractory Ovarian Carcinoma

Estimated

~$10 – $8,750

TeneoSeven, Inc.NCT07690189

Phase 2

Pembrolizumab and GVD With ctDNA-guided Consolidation in Patients With Relapsed or Refractory Classic Hodgkin Lymphoma: A Multicenter Phase 2 Study of the University of California Hematologic Malignancies Consortium

This is a single arm, open-label, multicenter, phase II study of pembrolizumab (pembro), gemcitabine, vinorelbine, and liposomal doxorubicin (GVD) in patients …

Hodgkin Lymphoma, AdultRefractory Hodgkin LymphomaClassic Hodgkin Lymphoma

Estimated

~$10 – $7,500

Michael Spinner, MDNCT07021989

Phase 2

A Phase II Trial of Durvalumab With Gemcitabine and Cisplatin as Neoadjuvant Therapy for High-Risk Resectable Intrahepatic Cholangiocarcinoma

This phase II trial tests how well giving durvalumab with standard chemotherapy, gemcitabine and cisplatin, before surgery works in treating patients with high…

Resectable Intrahepatic Cholangiocarcinoma

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06050252

Observational

Ejaculatory-sparing Holmium Laser Enucleation of the Prostate (HoLEP) vs Standard HoLEP: a Randomized Controlled Trial

The objective of this study is to compare a new surgical technique for HoLEP that will allow for sparing of ejaculation post-HoLEP.

Enlarged Prostate (BPH)Enlarged Prostate With Lower Urinary Tract Symptoms

Estimated

~$10 – $6,250

Northwestern UniversityNCT07631286

University of California Minority Patient-Derived Xenograft (PDX) Development and Trial Center (UCaMP) to Reduce Cancer Health Disparities

This trial establishes patient-derived cancer xenografts in addressing cancer health and treatment disparities that disproportionately affect racial/ethnic min…

Bladder CarcinomaGastric CarcinomaLiver and Intrahepatic Bile Duct Carcinoma+2 more

Estimated

~$10 – $750

University of California, DavisNCT04410302

Observational

Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets): A Pragmatic, Multi-Center, Randomized Controlled Trial

In this pragmatic clinical trial, which will dovetail with Veterans' routine outpatient dialysis clinic visits in six VA medical centers, the investigators wil…

Chronic Kidney Disease (CKD) Stage 5Kidney Dysfunction Requiring Dialysis (KDRD)Dialysis Dependency

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT05465044

Phase 2

A Phase II Pilot Study of yttriuM-90 in Combination With capEcitabine and aTezolizumab for oligomEtastatic cOlorectal Cancer With unResectable lIver MeTastasEs (METEORITE)

BrUOG-430 is a prospective, single-arm, phase 2 trial evaluating yttrium-90 radioembolization in combination with capecitabine and atezolizumab for the treatme…

Colorectal Carcinoma Metastatic in the Liver

Estimated

~$10 – $6,250

Brown UniversityNCT06555133

Observational

EarFlo: A Non-Invasive Treatment for Otitis Media With Effusion & Eustachian Tube Dysfunction in Adults

This study evaluates the use of the EarFlo device in adults with clinically confirmed Eustachian tube dysfunction and/or otitis media with effusion. The purpos…

Otitis Media With Effusion (OME)Eustachian Tube DysfunctionOtitis Media With Effusion

Estimated

~$10 – $7,500

Philip PerezNCT07777302

Phase 1

Effect of CYP2B6 Genotype and Efavirenz on the Disposition and Pharmacodynamic of Methadone and Tizanidine in Healthy Volunteers

The main goal of this clinical study is to test how CYP2B6 genetic variations and efavirenz (cornerstone in HIV-1 therapy) dictate the disposition (PK) of CYP2…

Drug-Drug Interaction

Estimated

~$10 – $6,250

Indiana UniversityNCT05789173

Phase 3

A Phase III, Randomised, Double-blind, Placebo-controlled Study to Assess the Efficacy, Safety, and Tolerability of BI 1291583 2.5 mg Administered Once Daily for up to 76 Weeks in Patients With Bronchiectasis (The AIRTIVITY™ Study)

This study is open to adults and adolescents aged 12 to under 18 with bronchiectasis. People can participate in this study if they produce sputum and have had …

Bronchiectasis

Estimated

~$10 – $7,500

Boehringer IngelheimNCT06872892

Phase 1

Phase 1b Window-of-Opportunity Study Evaluating CDK7 Inhibition in Patients With Localized Basal Pancreatic Cancer

The purpose of this study is to evaluate the safety and efficacy of samuraciclib in patients with localized pancreatic cancer.

Resectable Pancreatic Ductal AdenocarcinomaBorderline Resectable Pancreatic Ductal AdenocarcinomaLocally Advanced Pancreatic Ductal Adenocarcinoma

Estimated

~$10 – $6,250

University of WashingtonNCT07645651

Phase 1

A Phase I/II Study of Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab in Advanced Solid Tumors (PNeoVCA)

This phase I/II trial tests the safety and tolerability of an experimental personalized vaccine when given by itself and with pembrolizumab in treating patient…

Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+98 more