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4,630 recruiting studies matching your filters

Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)

This study evaluates the rates of radiation-specific toxicity, quality of life, and oncologic outcomes for early-stage breast cancer and ductal carcinoma in si…

Breast CancerEarly-stage Breast CancerDuctal Carcinoma in Situ+1 more

Estimated

~$10 – $6,250

UNC Lineberger Comprehensive Cancer CenterNCT06902311

Observational

Adapting a Group Intervention for Emotion Dysregulation in Autism and Intellectual Disability

The goal of this study is to help children with autism and a co-occurring intellectual disability and their families learn practical strategies for managing is…

AutismIntellectual Disabilities With Other Behavioral SymptomsIntellectual Disability

Estimated

~$10 – $6,250

Children's Mercy Hospital Kansas CityNCT07624448

Phase 2

A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab and Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy

The NSABP FC-13 study is being done to determine if using immunotherapies alone or in combination with other drugs will delay or prevent colorectal cancer from…

Colo-rectal Cancer

Estimated

~$10 – $6,250

NSABP Foundation IncNCT07058012

Observational

Retrograde Versus Antegrade Perfusion in Low-Moderate Hypothermia for Aortic Arch Surgery

The purpose of this study is to compare brain function after surgical circulatory arrest using either antegrade perfusion or retrograde perfusion.

Brain FunctionHemiarch Cardiac Procedure

Estimated

~$10 – $6,250

Duke UniversityNCT06986967

Phase 1

Phase I Trial of ATR Inhibitor Camonsertib Combined With Stereotactic Body Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

This phase I trial tests the safety, side effects, and best dose of camonsertib in combination with stereotactic body radiation therapy in controlling disease …

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Recurrent Head and Neck Squamous Cell CarcinomaRecurrent Hypopharyngeal Squamous Cell Carcinoma+27 more

Phase 3

A Randomised, Double-blind, Placebo-controlled, Parallel Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Adults with Mo…

Chronic Obstructive Pulmonary Disease (COPD)

Estimated

~$10 – $7,500

AstraZenecaNCT06883305

Phase 1

An Open-Label, Pilot Clinical Trial To Test The Safety And Feasibility Of Intestinal Microbiota Transplantation In Patients Undergoing Colon Resection

This is a single-center, open-label study for safety and feasibility of IMT in patients undergoing colonic surgery. After consent, individuals of the ages of 1…

Recurrent Clostridioides Difficile InfectionColonic Surgery

Estimated

~$10 – $6,250

University of MinnesotaNCT06370884

Pediatric Ovarian Tissue Banking - Operative Specimens From Females 0-18 Years of Age

A child is eligible to participate in this study because she is having surgery on her ovary. The investigators may obtain a sample of any discarded tissue from…

Benign Cysts OvarianCystectomyTorsion+1 more

Estimated

~$10 – $750

Ann & Robert H Lurie Children's Hospital of ChicagoNCT04118712

Phase 1

First-In-Human Phase 1b/2a Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adult Participants With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization

This is a first-in-human, Phase 1b/2a, open-label, dose-escalation study of a single treatment course consisting of multiple intradetrusor injections of EG110A…

Neurogenic Detrusor OveractivitySpinal Cord Injuries

Estimated

~$10 – $8,750

Cyllene TherapeuticsNCT06596291

International Rapid-onset Obesity With Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD) REDCap Registry

The Center for Autonomic Medicine in Pediatrics (CAMP) has collaborated with doctors from around the world to build the first International ROHHAD (Rapid-onset…

ROHHADRapid-Onset Obesity With Hypothalamic Dysfunction, Hypoventilation & Autonomic Dysregulation

Estimated

~$10 – $1,125

Ilya KhaytinNCT03135730

Phase 4

A Multi-Center, Single-Arm, Open-Label, Prospective, Phase 4 Study to Investigate the Safety and Efficacy of Rapidly Restarting Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide (B/F/TAF) in Viremic and Virologically-Suppressed Male and Female HIV-Positive Patients Aged ≥18 Years Who Are Treatment-Experienced and Returning to Care After Experiencing a Treatment Interruption of ≥12 Weeks

Managing HIV well requires taking antiretroviral therapy (ART) every day, but many people living with HIV experience interruptions in their treatment. These pa…

HIV -1 InfectionHIV (Human Immunodeficiency Virus)HIV+1 more

Estimated

~$10 – $7,500

CAN Community HealthNCT07476339

Phase 2

A Phase II Safety and Efficacy Study of Selinexor in Combination With Bispecific Antibody in Patients With Relapsed/Refractory Multiple Myeloma

The primary objectives of this study are to determine the safety of single agent Selinexor given with commercial bispecific antibody therapy in patients with R…

Multiple Myeloma in RelapseMultiple Myeloma, Refractory

Estimated

~$10 – $6,250

Duke UniversityNCT06822972