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A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients with Refractory Advanced/Metastatic Microsatellite Stable Colore…

Colorectal Cancer

Estimated

~$10 – $8,750

Criterium, Inc.NCT06992258

Abbott Structural Heart Device Registry

The Abbott Structural Heart (SH) Registry is being conducted to confirm the safety and performance of Abbott's SH devices in a post-market, real-world setting.…

Heart DiseasesASD - Atrial Septal DefectVSD - Muscular Ventricular Septal Defect+3 more

Estimated

~$10 – $1,125

Abbott Medical DevicesNCT06590467

The Study of Chronic Obstructive Pulmonary Disease (COPD) Participants Treated With Dupilumab (STRIDE) Registry

The STRIDE Registry will evaluate the real-world effectiveness and safety of dupilumab in participants with COPD. The primary objective is to describe characte…

COPD (Chronic Obstructive Pulmonary Disease)

A Pilot Trial to Evaluate the Effectiveness of Navigation, Interactive Web Education, or the Combination of Both to Promote Guideline-Concordant Colorectal Cancer Surveillance Care

This pilot clinical trial looks at whether patient navigation services, an interactive web education intervention, called Current Together After Cancer (CTAC),…

Stage I Colorectal Cancer AJCC v8Stage II Colorectal Cancer AJCC v8Stage III Colorectal Cancer AJCC v8

Estimated

~$10 – $6,250

Fred Hutchinson Cancer CenterNCT06995924

Natural History of Tuberculosis

Background: \- Tuberculosis (TB) is an infectious disease that affects numerous people worldwide. Researchers are interested in actively recruiting individual…

Mycobacterium InfectionsTuberculosis, Multidrug-ResistantLatent Tuberculosis+2 more

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT01212003

Phase 1

A Phase 1 Trial of miRisten in Adult Patients With Relapsed/Refractory AML

This phase I trial tests the safety, side effects, and best dose of miRisten in treating patients with acute myeloid leukemia (AML) that has come back after a …

Recurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT07025564

Observational

Effectiveness of an Individualized Progressive Treatment for Expanding Sound Tolerance in Adults With Autism Spectrum Disorder: A Crossover Randomized Controlled Trial (RCT)

The main goal of this clinical trial is to evaluate the effectiveness, benefits, and post-treatment persistence of an intervention for loudness hyperacusis in …

Loudness HyperacusisAutism Spectrum Disorder (ASD)Hyperacusis

Estimated

~$10 – $6,250

University of Central FloridaNCT07798297

Phase 1

Phase 1b/2 Study of Intratumoral MMR Vaccine Injection in Borderline Resectable/Unresectable Pancreatic Cancer

By doing this study, it is the hope to learn whether an injection of the measles, mumps, rubella (MMR) vaccine developed by Merck \& Co. (Merck's M-M-R® II) in…

Borderline Resectable/Unresectable Pancreatic CancerNon Metastatic Pancreatic Cancer

Estimated

~$10 – $6,250

University of ArkansasNCT07539155

Phase 4

Personalizing Heart Failure Treatment With Genomics: A Clinical Trial to Understand the Mechanisms and Validate a Polygenic Risk Score for Beta-Blocker Response

The purpose of this trial is to better understand how the beta-blocker metoprolol works in people with Heart Failure with Reduced Ejection Fraction (HFrEF) acc…

Heart Failure With Reduced Ejection Fraction

Estimated

~$10 – $6,250

University of MichiganNCT07490067

Phase 2

Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial

The long-term goal is to test the clinical efficacy of senolytic therapies to reduce progression to and severity of sepsis in older patients. The central hypot…

SepsisAcute InfectionOrgan Failure

Estimated

~$10 – $6,250

University of MinnesotaNCT05758246

Phase 1

Randomized Clinical Trial of the Application of TrachPhone HME and the Impact on Patient Satisfaction for Tracheostomized Head and Neck Cancer Patients

This study is being conducted at Tampa General Hospital. This study aims to evaluate the effectiveness of TrachPhone Heat Moisture Exchange (HME) on both patie…

Patient SatisfactionPulmonary Rehabilitation

Estimated

~$10 – $6,250

University of South FloridaNCT07798414

Exploring the Use of Tumor Informed Circulating Tumor DNA (ctDNA) in High Grade Upper Tract Urothelial Cancer (UTUC)

The study will evaluate the feasibility of collecting ctDNA data for UTUC patients in perioperative setting and if the data generated can help with design of f…

Upper Tract Urothelial Carcinoma

Estimated

~$10 – $750

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT07793240