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Phase 2
An Open Label Evaluation of Intralesional Injection of Sodium Thiosulfate in the Treatment of Cutaneous or Tendon Calcinosis in Connective Tissue Disease
The specific objective of this study is to perform a small, open-label study to assess the safety and efficacy of intralesional, subcutaneous injection of STS …
Systemic Sclerosis (SSc)DermatomyositisMixed Connective Tissue Disease (MCTD)+1 more
Robyn T. Domsic, MD, MPHNCT06672822
Quantification of Calcinosis Cutis Disease Burden in Patients With Systemic Sclerosis Using Computed Tomography Images
The main purpose of this study is to develop sensitive radiographic measurement techniques that can be used as outcome measures along with patient-reported out…
Systemic Sclerosis (SSc)Calcinosis Cutis
Yale UniversityNCT07228429
A Natural History Study of Bone and Mineral Disorders
This study has four objectives: 1) to provide investigators the opportunity to study bone specimens from patients with various skeletal diseases; 2) to treat p…
Tumor Induced OsteomalciaOsteomalaciaFamilial Tumoral Calcinosis
National Institute of Dental and Craniofacial Research (NIDCR)NCT00024804