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77 recruiting studies matching your filters

A Phase IIa, Non-Randomized, Open-Label Dose Expansion Trial of Isunakinra in Combination With Pembrolizumab in Patients With Metastatic or Unresectable, Locally Advanced Colorectal Cancer

This study will enroll patients with colorectal cancer that is locally advanced or metastatic. The tumor must be microsatellite stable (MSS), have a tumor muta…

Colorectal Cancer Metastatic

Estimated

~$10 – $8,750

Buzzard PharmaceuticalsNCT06634875

Observational

Contribution of Race to Nutritional Approach to Lower Cardiovascular Risk Factors in Men Undergoing Androgen Deprivation Therapy

There is a well-documented association between androgen deprivation therapy (ADT) and cardiovascular morbidity. A majority of men on ADT gain weight contributi…

Prostate Cancer Metastatic Disease

Estimated

~$10 – $6,250

University of California, Los AngelesNCT06682390

Phase 1

A Phase 1a/1b, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Evidence of Antitumor Activity of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors

Phase 1, open-label dose-escalation study to determine the MTD of INV-1120 and RP2D, and to assess the DLT of INV-1120 as a single agent or in the combination …

CancerSolid Tumor, AdultCancer Metastatic+3 more

Estimated

~$10 – $8,750

Shenzhen Ionova Life Sciences Co., Ltd.NCT04443088

Phase 1

Phase I Dose-Escalating Study of Combining Intravenous Tirapazamine and Transarterial Embolization (TAE) in Liver Cancer

This phase 1 study is to determine the optimal dose and tolerability of a hypoxia-activating agent, tirapazamine, when it is combined with embolization in live…

Hepatocellular CarcinomaGastrointestinal Cancer MetastaticNeuroendocrine Tumors

Estimated

~$10 – $8,750

Teclison Ltd.NCT02174549

A Prospective Study of the IlluminOss Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pathological Fractures in the Pelvis From Metastatic Bone Disease or Geriatric Pelvic Fractures

The aim of this project is to assess the effectiveness of the IlluminOss pelvic implants in patients with pelvic metastatic disease presenting with pain, risk …

Cancer MetastaticTraumaPathologic Fracture

Estimated

~$10 – $750

Massachusetts General HospitalNCT04842266