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7 recruiting studies matching your filters

Safety and Efficacy of OTL78 (Zopocianine), a Prostate-Specific Membrane Antigen (PSMA)-Targeted Fluorescent Agent, for Intraoperative Imaging of Prostate Cancer: A Phase IIb Trial

This study is being done to support the selection of single dose and timing regimen of Zopocianine (OTL78) in combination with Near InfraRed (NIR) fluorescent …

Prostate Cancer SurgeryProstate Cancer Metastatic Disease

Estimated

~$10 – $7,500

Clinton BahlerNCT07725523

Observational

Development and Implementation of Pilot Postoperative Guidelines to Improve Functional Outcomes Following High-Risk Surgery for Cancer: A North American Prospective Feasibility Study

The objective of this study is to develop and evaluate the implementation of novel timeline-specific National Comprehensive Cancer Network (NCCN)-style clinica…

CancerAbdominal Cancer SurgerySurgery+2 more

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT07720089

Observational

ColoSeal™ ICD System Anastomotic Protection Pivotal Study

The purpose of this clinical investigation is to evaluate the safety of the ColoSeal ICD System by evaluating its effectiveness in reducing the stoma creation …

Rectal Cancer Surgery

Estimated

~$10 – $8,750

Averto Medical, Inc.NCT07429110

Long-term Oncologic Safety of Nipple Sparing Mastectomy in Women With High Penetrance Germline Pathogenic Variants in Breast Cancer Susceptibility Genes

Patients with a germline pathogenic variant (GPV) in high-penetrance breast cancer susceptibility genes who are considering risk reducing mastectomy (RRM) ofte…

Breast Cancer Surgery

Estimated

~$10 – $750

Sir Mortimer B. Davis - Jewish General HospitalNCT06888388

Phase 2

Comparative Effectiveness of Intrapyloric Botulinum Toxin Injection Versus Pyloromyotomy for Pyloric Drainage During Esophagectomy: A Registry-Based, Pragmatic Randomized Noninferiority Trial

The goal of this pragmatic, registry-based, randomized clinical trial is to find out if using botulinum toxin (Botox) to help drain the stomach during an esoph…

Esophageal Cancer SurgeryEsophagectomyDelayed Gastric Emptying Following Procedure+4 more

Estimated

~$10 – $6,250

The Cleveland ClinicNCT06721520

Observational

Evaluating Optimal Perioperative Pain Management: A Prospective Randomized Control Trial of Laparoscopic Transversus Abdominis Plane Block With Local Anesthetic, Laparoscopic Transversus Abdominis Plane Block Alone, and Local Anesthetic Alone in Minimally Invasive Oncologic Surgery

This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally inv…

Oncologic SurgeryCancerCancer Surgery+8 more

Estimated

~$10 – $7,500

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)NCT06731998

Phase 1

Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for High Risk Localized and Locally Advanced Prostate Cancer: A Phase I/Ib Trial

The goal of this clinical trial is to determine the safety and feasibility of a new combination of darolutamide and relugolix as neoadjuvant therapy preceding …

Prostate CAProstate Cancer (Adenocarcinoma)Prostate Cancer Surgery

Estimated

~$10 – $7,500

AdventHealthNCT06631521