This study is a dynamically adjustable prospective longitudinal study designed to capture biospecimen (biopsy, blood, surgical) and multimodal treatment-relate…

Locally Advanced Cervical CarcinomaLocally Advanced Cervical CancerLocally Advanced Pancreas Cancer+7 more

~Estimated

~$10 – $6,250

Washington University School of MedicineNCT05975593

Phase 2

Phase II Study of Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma

Advanced pancreatic cancer patients receiving treatment of adaptive stereotactic body radiotherapy (SBRT) with concurrent and adjuvant defactinib plus avutomet…

Pancreatic AdenocarcinomaCancer of the PancreasPancreas Cancer+1 more

~Estimated

~$10 – $6,250

Washington University School of MedicineNCT07126158

Phase 1

Phase I Trial of MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

The investigators hypothesize that MK2 inhibition may improve efficacy of mFOLFIRINOX chemotherapy for patients with pancreatic ductal adenocarcinoma (PDAC).

Metastatic Pancreatic Ductal AdenocarcinomaPancreatic CancerCancer of the Pancreas

~Estimated

~$10 – $6,250

Washington University School of MedicineNCT06648434