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Observational
MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial (METEOR-CRATR)
This study is a dynamically adjustable prospective longitudinal study designed to capture biospecimen (biopsy, blood, surgical) and multimodal treatment-relate…
Locally Advanced Cervical CarcinomaLocally Advanced Cervical CancerLocally Advanced Pancreas Cancer+7 more
Washington University School of MedicineNCT05975593
Phase 2
Phase II Study of Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma
Advanced pancreatic cancer patients receiving treatment of adaptive stereotactic body radiotherapy (SBRT) with concurrent and adjuvant defactinib plus avutomet…
Pancreatic AdenocarcinomaCancer of the PancreasPancreas Cancer+1 more
Washington University School of MedicineNCT07126158
Phase 1
Phase I Trial of MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma
The investigators hypothesize that MK2 inhibition may improve efficacy of mFOLFIRINOX chemotherapy for patients with pancreatic ductal adenocarcinoma (PDAC).
Metastatic Pancreatic Ductal AdenocarcinomaPancreatic CancerCancer of the Pancreas
Washington University School of MedicineNCT06648434