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103 recruiting studies matching your filters

A Multi-Institutional Phase 2 Evaluation of Daraxonrasib in Recurrent KRAS-Mutant Biliary Tract Cancer

The purpose of this study is to evaluate the anti-tumor efficacy of daraxonrasib monotherapy in patients with unresectable or advanced/metastatic, KRAS-mutant …

Biliary Tract CancersIntrahepatic Cholangiocarcinoma (Icc)Extrahepatic Cholangiocarcinoma+3 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT07793253

Phase 1

A Pilot Study of Targeting Driver Oncogenes With a Peptide Vaccine Plus Durvalumab and Tremelimumab for Patients With Biliary Tract Cancers

The purpose of this study is to evaluate the safety and the immune response of personalized mutant peptide vaccine with poly-ICLC adjuvant (mBTCvax) in combina…

Biliary Tract Cancers

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT06564623

Phase 1

A Phase 1/2 Open-Label, Multiple-Dose, Dose-Escalation Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of VMD-928 as Monotherapy and in Combination With Pembrolizumab in Subjects With Solid Tumors or Lymphoma

This is a multicenter, open-label, Phase 1/2 study of orally administered VMD-928 monotherapy and in combination with pembrolizumab in adult subjects with adva…

Head and Neck CarcinomaAdenoid Cystic CarcinomaLung Cancer+22 more

Estimated

~$150 – $4,200

Phase 1

Liposomal Irinotecan (Nal-IRI) Plus 5-fluorouracil and Leucovorin (5-FU/LV) Plus Oxaliplatin (NALIRIFOX) as First-Line Chemotherapy for Patients With Advanced Small Intestine and Appendiceal Cancers

This study will evaluate the safety and efficacy of NALIRIFOX per NAPOLI-3 regimen as first-line chemotherapy for patients with advanced small intestine and ap…

Advanced Small Intestine CancerAppendiceal Cancers

Estimated

~$150 – $3,000

Actual pay is set by the research site.

The Methodist Hospital Research InstituteNCT07060014

Phase 2

A Phase 1b Dose Escalation and Expansion Study of IMGN151 as Monotherapy and in Combination With Other Anti-Cancer Therapies in Subjects With Gynecologic Cancers

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess safety and tolerability …

Gynecologic CancersPlatinum-Sensitive Ovarian CancerFallopian Tube Cancer+1 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

AbbVieNCT07024784

Phase 2

Brachytherapy Fractionation Individualized by Treatment Feasibility in Cervical Cancer: Phase II Trial Comparison of 3 vs 4 Fractions (BRACHY-FIT).

This is a prospective non-randomized clinical trial to evaluate the feasibility of 3 fraction versus a standard 4 fraction high dose rate brachytherapy regimen…

Cervical Cancers

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Stanford UniversityNCT07022470

Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers

The purpose of this study is to identify and confirm new blood and tissue markers for prognosis and tumor hypoxia. Tumor hypoxia, or the condition of low oxyge…

Head and Neck CancerLung CancerLip Cancer+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Stanford UniversityNCT00568490

Follow-Up Evaluation for Gene-Therapy Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical Trials

Background: \- Gene therapy involves changing the genes inside the body s cells to stop disease. It is very closely regulated. People who have had this therap…

Pediatric CancersHematologic MalignanciesSolid Tumors

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT02315599

Prospective Data Registry and Quality of Life Assessment of PatientsUndergoing Radiotherapy With the RefleXion Medical Radiotherapy System (PREMIER Registry)

The purpose of this prospective cohort study is to assess clinical and quality of life measures as well as to define the severity of adverse effects for the us…

CancerCancer Central Nervous SystemCancer Thoracic+5 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

RefleXion MedicalNCT05406167

Phase 1

A Phase 1 Open-Label Study to Evaluate the Efficacy and Safety of ABBV-400 in Select Advanced Solid Tumor Indications

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess adverse events and chang…

Hepatocellular CarcinomaPancreatic Ductal AdenocarcinomaBiliary Tract Cancers+5 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

AbbVieNCT06084481

Phase 2

Sacituzumab Tirumotecan to Treat Patients With Brain Metastases From Triple-negative Breast Cancer

This is a multi-site prospective single-arm open-label phase 2 clinical trial including 20 participants with metastatic TNBC and active brain metastases to be …

Metastatic Triple Negative Breast Cancers

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Yale UniversityNCT07458113

Observational

The Effectiveness of Screening Women With Lower Genital Tract Neoplasia or Cancers for Anal Cancer Precursors

The goal of this single arm trial is to prospectively evaluate screening methods for anal cancer precursors in HIV uninfected women with a history of lower gen…

Estimated

~$10 – $750

Actual pay is set by the research site.

Icahn School of Medicine at Mount SinaiNCT05217940