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6 recruiting studies matching your filters

A Phase 3, Multicenter, Randomized, Open-label, Controlled Study to Investigate the Efficacy and Safety of 4-Factor Prothrombin Complex Concentrate in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass

This is a phase 3, multicenter, randomized, open-label, parallel-group, controlled study to assess the efficacy and safety of BE1116 compared with fresh frozen…

Complex Cardiovascular Surgery With Cardiopulmonary Bypass

Estimated

~$10 – $7,500

CSL BehringNCT07094087

Observational

Personalized (Demand-Informed) Blood Transfusion Protocol for Cardiac Patients

This study compares two accepted ways of deciding when adults recovering from open-heart surgery should receive a blood transfusion in the intensive care unit.…

Cardiac SurgeryBlood TransfusionAnemia+1 more

Estimated

~$10 – $7,500

Yan Mia MinNCT07671469

Phase 3

Effect of Inhaled Nitric Oxide on Major Adverse Events Requiring Intensive Life Support in Adults Undergoing Cardiac Surgery With Cardiopulmonary Bypass: A Phase III, Double-Blind, Multicenter, Randomized Controlled Trial (Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass, the NORISC Trial)

Cardiac surgery is a procedure that is commonly performed worldwide. Despite these technological advances, cardiac surgery remains a high-risk surgery. Among p…

Nitric OxideCardiac SurgeryCardiopulmonary Bypass+1 more

Estimated

~$10 – $6,250

Xijing HospitalNCT06702553

Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)

Acute lung injury (ALI) following cardiopulmonary bypass (CPB) is a serious complication, often prolonging the length of stay in ICU and potentially dealing to…

Lung InjuryCardiopulmonary Bypass

Estimated

~$10 – $1,125

Sophia KoutsogiannakiNCT04296071

A Comparison of Renal vs Limb NIRS for Predicting Cardiac Surgery Associated Acute Kidney Injury

Acute kidney injury (AKI) is a complication of cardiac surgery that can affect outcome. Near Infrared Spectroscopy (NIRS) is a technology that uses light to de…

NIRSCardiac Surgery Associated - Acute Kidney InjuryCardiac Surgery Requiring Cardiopulmonary Bypass+1 more

Estimated

~$10 – $750

University of UtahNCT06705855

The Association Between Tau & GFAP and Postoperative Neurological Impairment in Patients Undergoing Cardiac Surgery

Patients born with heart defects often undergo surgical procedures on a heart lung machine. With improvements in medical and surgical management, their surviva…

Cardiac Surgery Requiring Cardiopulmonary BypassBrain InjuryCongenital Heart Defect

Estimated

~$10 – $750

Boston Children's HospitalNCT06899971