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3 recruiting studies matching your filters
Phase 1
A Phase 1, Open-Label, Multicenter Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer
This study is a first-in-human, Phase 1, open-label, multicenter study to assess the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD), and the …
Prostate CancerMetastatic Castration-resistant Prostate CancerCastration Resistant Prostatic Cancer
Janux TherapeuticsNCT05519449
Phase 1
A Phase 1/1b First-in-Human, Open Label, Dose Escalation and Cohort Expansion Study of MGC026 in Participants With Advanced Solid Tumors
The study is designed to understand the safety, tolerability, pharmacokinetics, immunogenicity, and preliminary antitumor activity of MGC026 in participants wi…
Advanced Solid TumorAdvanced CancerMetastatic Cancer+19 more
MacroGenicsNCT06242470
Phase 2
A Phase II Trial of FASN Inhibition by Omeprazole in Combination With Cabazitaxel in Patients With Docetaxel- and Castration-Resistant Prostate Cancer
The purpose of this research study is to find out what effects (good and bad) omeprazole and cabazitaxel, or omeprazole and docetaxel, has on participants and …
Prostate CancerRefractory CancerCastration Resistant Prostatic Cancer
Wake Forest University Health SciencesNCT04337580