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4 recruiting studies matching your filters
Phase 1
An Open-label Multicenter Phase 1b-2 Study of Elacestrant in Combination With Abemaciclib in Women and Men With Brain Metastasis From Estrogen Receptor Positive, HER-2 Negative Breast Cancer
This is a multi-site, global, open-label study that includes a phase 1b evaluation of elacestrant in combination with abemaciclib in women and men with brain m…
Breast NeoplasmsBrain NeoplasmsNeoplasms by Site+5 more
Estimated
~$10 – $8,750
Stemline Therapeutics, Inc.NCT05386108
Phase 1
Phase 1 Trial of Engineered HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors
This study is a clinical trial to determine the safety of inoculating G207 (an experimental virus therapy) into a recurrent or refractory cerebellar brain tumo…
Neoplasms, BrainGlioblastoma MultiformeGlioblastoma of Cerebellum+30 more
Estimated
~$10 – $6,250
Phase 1
A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
The primary objective of this Phase 1, open-label, dose-escalation, and exploratory study is to evaluate the safety and tolerability profile (establish the max…
Central Nervous System NeoplasmsGlioblastomaGliosarcoma, Adult+20 more
Estimated
~$10 – $8,750
Jazz Pharmaceuticals
Phase 1
A Phase 1/1b Study of Autologous b7-h3 Chimeric Antigen Receptor t Cells (b7-h3.cd28z.Cart) in Children and Young Adults With Recurrent or Progressive Cns Neoplasms Expressing b7-h3 Target
The purpose of this research study is to test the safety and effectiveness of a cell therapy at different doses for children and young adults with recurrent or…
Central Nervous System NeoplasmsBrain TumorBrain Tumor, Recurrent+11 more
Estimated
~$10 – $7,500
Robbie MajznerNCT07390539