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4 recruiting studies matching your filters
Phase 1
Phase 1/Phase 2 Open Label Trial of a Novel Indenoisoquinolone C-MYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
Background: Glioblastoma is a common brain cancer in adults. Treatment includes surgery, radiation, and chemotherapy. But this cancer can return after treatme…
Recurrent GlioblastomaGlioblastoma IDH (Isocitrate Dehydrogenase) WildtypeRelapsed Cancer+12 more
Estimated
~$10 – $5,625
National Institute of Neurological Disorders and Stroke (NINDS)NCT07416188
Genomes for Kids (G4K)
The development of next generation sequencing (NGS) techniques, including whole genome (WGS), exome (WES) and RNA sequencing has revolutionized the ability of …
Solid, Liquid, Central Nervous System Tumors
Estimated
~$10 – $750
St. Jude Children's Research HospitalNCT02530658
Phase 1
Phase 1/2 Trial of Mirdametinib in Patients With MAPK Pathway Mutant Central Nervous System Tumors
The purpose of this study to find out whether mirdametinib is a safe and effective treatment for Central Nervous System/CNS tumors (glioma and neurohistiocytos…
Central Nervous System TumorsGlioma
Estimated
~$10 – $6,250
Memorial Sloan Kettering Cancer CenterNCT07539441
Phase 1
A Pilot Study to Assess the Safety, Feasibility, and Preliminary Efficacy of a Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors
The purpose of this research study is to learn about the safety and feasibility of giving a personalized DNA vaccine to people with central nervous system tumo…
Pediatric Recurrent Central Nervous System Tumors
Estimated
~$10 – $6,250
Washington University School of MedicineNCT03988283