Browse Studies — Arctuva

Phase 1

Window of Opportunity Trial of Fenofibrate in Patients With High-grade Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma

Normally, p53 helps prevent tumors from forming in the body. Early studies have shown that Fenofibrate, a cholesterol-lowering drug, can restore normal functio…

Cervical Intraepithelial NeoplasiaInvasive Cervical Cancer

Estimated

~$10 – $7,500

Lindsay Ferguson, MDNCT06191133

Phase 1

A Phase I Open Label, Dose Escalation Clinical Trial Assessing the Safety, Tolerability, and Feasibility of pNGVL4aCRTE6E7L2 HPV DNA Vaccine Administration Via Intramuscular TriGridTM Electroporation Delivery System to Patients With HPV16-Positive High-Grade Cervical Intraepithelial Neoplasia

The primary goal of this phase I open label study is to determine the safety and tolerability of pNGVL4aCRTE6E7L2 DNA vaccine, as administered by intramuscular…

Human Papillomavirus Type 16Cervical Intraepithelial Neoplasia Grade IICervical Intraepithelial Neoplasia, Grade III

Estimated

~$10 – $6,250

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT04131413

Phase 2

A Phase II Open-Label, Single Arm Pilot Study to Evaluate the Safety and Efficacy of Pembrolizumab for High-Grade Cervical Intraepithelial Neoplasia

This phase II trial studies the effect of pembrolizumab on cervical intraepithelial neoplasia. Immunotherapy with monoclonal antibodies, such as pembrolizumab,…

Cervical Intraepithelial NeoplasiaCervical Squamous Cell Carcinoma In SituCervical Squamous Intraepithelial Neoplasia 2

Estimated

~$10 – $6,250

Jonsson Comprehensive Cancer CenterNCT04712851

Phase 2

PVX4 for the Treatment of Human Papilloma Virus (HPV)16+ Cervical Dysplasia

The purpose of this Phase 2 study is to compare the effects of administering the PVX4 combination device biologic product (pBI-4 DNA vaccine via electroporatio…

Cervical Intraepithelial Neoplasia Grade 2/3Human Papilloma Virus Infection Type 16

Estimated

~$10 – $8,750

PapiVax Biotech, Inc.NCT07454915

Phase 4

Prospective Observational Immunogenicity Trial of Gardasil-9 HPV Vaccine in People Living With Adequately Managed HIV

The primary objective of this study is to determine the magnitude and breadth of the serum antibody response to the nonavalent HPV vaccine (Gardasil-9) in adul…

Papillomavirus VaccinesHuman Immunodeficiency VirusPapillomavirus Infection+4 more

Estimated

~$10 – $6,250

Louisiana State University Health Sciences Center in New OrleansNCT05266898