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A Phase 1/1b Study of Autologous b7-h3 Chimeric Antigen Receptor t Cells (b7-h3.cd28z.Cart) in Children and Young Adults With Recurrent or Progressive Cns Neoplasms Expressing b7-h3 Target
The purpose of this research study is to test the safety and effectiveness of a cell therapy at different doses for children and young adults with recurrent or…
Cognitive Control Targets for the Treatment of Obsessive Compulsive Disorder in Young Children
This study aims to examine the effects of a game-like program called cognitive control training (CT) for children with obsessive compulsive disorder (OCD). Chi…
Examining the Preliminary Efficacy of an In-Person Lifestyle Intervention for Black Female Adolescent/Caregiver Dyads at Risk for Type 2 Diabetes Mellitus
The aim of this study is to look at changes in diabetes-related risk factors in Black adolescent girls who are at risk for type 2 diabetes and their primary fe…
Addressing Appetitive Traits to Promote Weight Management in Children Who Overeat
The objective of this proposed study is to compare Regulation of Cues (ROC), Family-Based Treatment (FBT), ROC+ nutrition education and reducing energy intake …
The Impact of Stress and Caregiver Sensitivity on Infant Cellular Aging in a Population of Under-Resourced Families: A Randomized Controlled Trial
The goal of this clinical trial study is to learn how stress in childhood, or Early Life Adversity (ELA), gets "under the skin" and influences long-term health…
Measuring Aided Language Development
The focus of the current study is to systematically investigate the psychometric properties of a range of aided language measures, which are based on the Graph…
Fostering Patient-oriented Research in Cardiometabolic Disease Pathogenesis and Prevention
The goal of this study is to 1) use magnetic resonance imaging (MRI) to evaluate the effect of nutritious foods on inflammation in the human hypothalamus of ch…
Bedside Notes: A Multicenter Trial to Improve Family Clinical Note Access and Outcomes for Hospitalized Children
This study will test if giving parents access to their child's medical notes on a bedside tablet: * helps them get more involved in their care * helps identif…
The Project: EveryChild Protocol: A Registry, Eligibility Screening, Biology and Outcome Study
This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patien…
More Outside Your Door (MOYD): a Multilevel Intervention Promoting Traditional Diet and Physical Activity to Decrease Risk of Obesity in Alaska Native (AN) Preschoolers
The preschool age is a crucial period of growth and an optimal time to begin to establish healthy eating and physical activity habits leading to better food an…
Evaluation of Circles of Safety for the Primary Prevention of Child Sexual Abuse
Using a matched cluster randomized control design, the proposed study will evaluate a child sexual abuse (CSA) primary prevention strategy, Circles of Safety®.…
Mobile Apps for Preschool Parents (MAPP) Study
The purpose of Mobile Apps for Preschool Parents (MAPP) Study is to test the effectiveness of two mobile applications for parents of preschool aged children: 1…