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1,174 recruiting studies matching your filters

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 2) (IRIS-CKD)

IRIS-CKD is a two-program implementation study to improve guideline-recommended screening and treatment of chronic kidney disease (CKD) in individuals with typ…

Chronic Kidney Disease(CKD)Type 2 DMType 2 Diabetes Mellitus (T2DM)

Estimated

~$10 – $6,250

Duke UniversityNCT06906640

Phase 3

Randomized, Phase III Study of Early Intervention With Venetoclax and Obinutuzumab Versus Delayed Therapy With Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): EVOLVE CLL/SLL Study

This phase III trial compares early treatment with venetoclax and obinutuzumab versus delayed treatment with venetoclax and obinutuzumab in patients with newly…

Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT04269902

Observational

Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation (PEACE) Intervention

Chronic Obstructive Pulmonary Disease (COPD) is a serious lung condition that affects millions of people in the United States. Each year, it leads to about 150…

COPD (Chronic Obstructive Pulmonary Disease)

Estimated

~$10 – $6,250

University of Massachusetts, WorcesterNCT07072039

Observational

A Prospective, Multi-center Clinical Study to Evaluate the Safety and Effectiveness of Arcevo LSA in the Open Repair of Aortic Arch Aneurysms and Dissections

The goal of this clinical trial is to learn if the Arcevo LSA stent graft can safely and effectively treat patients that have an acute or chronic aortic dissec…

Aortic Arch AneurysmAortic Arch DissectionChronic Aortic Dissection+1 more

Estimated

~$10 – $8,750

Artivion Inc.NCT07089576

Phase 3

A Randomized, Double-blind, Parallel Group, Multi-center, Phase III Study to Assess the Efficacy of Budesonide, Glycopyrronium, and Formoterol Fumarate Metered Dose Inhaler Relative to Glycopyrronium and Formoterol Fumarate MDI on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease (THARROS)

This study will evaluate the effect of triple ICS/LAMA/LABA therapy with BGF MDI 320/14.4/9.6 μg on cardiopulmonary outcomes relative to LAMA/LABA therapy with…

COPD (Chronic Obstructive Pulmonary Disease)

Estimated

~$10 – $7,500

AstraZenecaNCT06283966

Phase 2

Randomized Phase 2 Study Comparing Acalabrutinib to Acalabrutinib and Obinutuzumab in the Treatment of Patients With Early-Stage Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Who Are at High Risk of Disease Progression

This phase II trials studies how well acalabrutinib with or without obinutuzumab works in treating patients with early-stage chronic lymphocytic leukemia or sm…

Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma

Estimated

~$10 – $6,250

Mayo ClinicNCT03516617

Observational

R01_PilotStudy2_Jaw Muscle Metabolic and Brain-Derived Phenotypes of Chronic TMD Pain

The proposed study will assess the effect of local heat therapy on jaw pain and jaw fatigue secondary to a teeth clenching task in chronic TMD pain cases. Rese…

Chronic TMD PainTemporomandibular Disorder

Estimated

~$10 – $6,250

University of MinnesotaNCT07153107

Phase 1

Phase I/II Study Using Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists

Background: Chronic granulomatous disease (CGD) affects the immune system. People with CGD are more likely to get infections. Drugs can help control infection…

Chronic Granulomatous Disease

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT05463133

Phase 1

A Phase 1, Multi-center, Single-dose, Open-label Study to Evaluate the Pharmacokinetics and Safety of Golcadomide (BMS-986369) in Participants With Severe Renal Impairment and End-Stage Renal Disease Compared With Participants With Normal Renal Function

The purpose of this study is to assess the pharmacokinetics and safety of golcadomide (BMS-986369) in matched healthy participants with normal renal function, …

Kidney Failure, Chronic

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT07763418

Phase 2

Phase II Study Assessing the Efficacy and Toxicity of Olverembatinib Monotherapy in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase

To learn if olverembatinib can help to control newly diagnosed CML in the chronic phase.

Chronic Myeloid Leukemia

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT06817720

Phase 2

Phase 2 Study of Golcadomide With Rituximab as a Bridging Therapy Prior to CAR-T for Patients With Relapsed or Primary Refractory Aggressive B-Cell Non-Hodgkin Lymphoma (NHL)

This phase II trial tests the effectiveness of golcadomide and rituximab as bridging treatment before chimeric antigen receptor (CAR) T-cell therapy in patient…

Large B-Cell Lymphoma With IRF4 RearrangementRecurrent Aggressive B-Cell Non-Hodgkin LymphomaRecurrent ALK-Positive Large B-Cell Lymphoma+28 more

A Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution in Children and Young Adults With Hematologic Malignancies

The use of venetoclax-based therapies for pediatric patients with relapsed or refractory malignancies is increasingly common outside of the clinical trial sett…

Hematologic MalignancyLeukemiaLymphoma+16 more

Estimated

~$10 – $675

Children's Hospital Medical Center, CincinnatiNCT06131801