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1,174 recruiting studies matching your filters

Nemtabrutinib and Pembrolizumab in Patients With Richter Transformation: A Phase II Study

This phase II trial tests how well nemtabrutinib in combination with pembrolizumab works in treating patients with Richter transformation, diffuse large B-cell…

Richter SyndromeDiffuse Large B-Cell LymphomaChronic Lymphocytic Leukemia

Estimated

~$10 – $7,500

Roswell Park Cancer InstituteNCT06863402

Phase 4

An Open Label Trial to Evaluate Efficacy and Safety of Roflumilast 0.3% Cream for Chronic Plaque and Nail Psoriasis

This is an open label trial in subjects ≥12 years of age and older with chronic plaque psoriasis and moderate to severe nail psoriasis. Eligible participants …

Chronic Plaque PsoriasisNail Psoriasis

Estimated

~$10 – $8,750

Modern Research Associates, PLLCNCT07725822

Phase 3

Phase III Evaluation of Fixed Duration Zanubrutinib Plus Sonrotoclax-Based Therapy Compared to Continuous Zanubrutinib in Previously Untreated Older Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

This phase III trial compares the effect of adding sonrotoclax to zanubrutinib versus zanubrutinib alone for the treatment of patients with untreated chronic l…

Chronic Lymphocytic LeukemiaSmall Lymphocytic Leukemia

Estimated

~$10 – $6,250

Alliance for Clinical Trials in OncologyNCT07321652

Phase 1

NADPH Oxidase Correction in mRNA Transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)

Background: CGD is caused by a gene mutation. For people with CGD, their cells cannot kill germs well, so they can get frequent or life-threatening infections…

Chronic Granulomatous DiseaseInfection

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT05189925

Observational

A Single-Session Pain Management Intervention for Severe Pain After Cesarean Delivery: A Pilot Feasibility Study

This pilot feasibility study will evaluate the feasibility and acceptability of delivering Empowered Relief (ER), a single-session pain management intervention…

Severe PainCesarean Section ComplicationsPostpartum+2 more

Estimated

~$10 – $6,250

Stanford UniversityNCT07832240

Phase 2

A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Clazakizumab in Reducing hsCRP in Adults With Elevated hsCRP and Established ASCVD or at Increased Risk for ASCVD Events

The purpose of this study is to measure the change in high-sensitivity C-reactive protein (hsCRP), a marker of inflammation in the body, with clazakizumab comp…

AtherosclerosisCardiovascular DiseaseObesity+3 more

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07783802

Phase 1

Phase I Study of Activated T-Cells Expressing Second or Third Generation CD19-Specific Chimeric Antigen Receptors for Advanced B-Cell Non-Hodgkin's Lymphoma, Acute Lymphocytic Leukemia and Chronic Lymphocytic Leukemia (SAGAN)

Subjects on this study have a type of lymph gland cancer called Non-Hodgkin Lymphoma, acute lymphocytic leukemia, or chronic Lymphocytic Leukemia (these diseas…

Non-Hodgkin LymphomaChronic Lymphocytic LeukemiaAcute Lymphocytic Leukemia

Estimated

~$10 – $6,250

Baylor College of MedicineNCT01853631

Phase 2Remote eligible

An Internet of Things Automated Cognitive Behavioral Therapy for Insomnia That Improves Cognition in Older Adults

This double blind randomized clinical trial on older independent-living healthy individuals with symptoms of insomnia will harness Cognitive Behavioral Therapy…

InsomniaInsomnia Chronic

Estimated

~$10 – $8,750

Proactive Life IncNCT07316153

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

Background: Bruton s tyrosine kinase inhibitors (BTKi) are used to treat a form of leukemia. But taking BTKi can also increase a person s risk of developing a…

Chronic Lymphocytic Leukemia (CLL)Waldenstr(SqrRoot)(Delta)m s MacroglobulinemiaMantle Cell Lymphoma+3 more

Estimated

~$10 – $675

National Heart, Lung, and Blood Institute (NHLBI)NCT05724121

Phase 3

An Open-label, Multi-Center, Single-arm Prospective Clinical Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Gamunex®-C Plus Standard Medical Treatment to Prevent Infections in Participants With Secondary Antibody Deficiency Associated With Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma

The main goal of this study is to show that people with certain immune problems (from Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma) …

Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma

Estimated

~$10 – $8,750

Grifols Biologicals, LLCNCT07582432

A Natural History Study of Metabolic Sizing in Health and Disease

Background: Scientists have long used simple measures (such as height and weight) to estimate how much a person s body uses food (calories) as energy, as comm…

Metabolic DisordersCancerChronic Kidney Disease+2 more

Estimated

~$10 – $675

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT05398783

Observational

Improving Medication Adherence Using an Adaptive mHealth Intervention in Adolescents With Asthma.

The primary objective is to examine the efficacy of an mHealth adherence intervention (Asthma Ctrl) on adherence to daily inhaled corticosteroids as measured b…

Asthma in ChildrenAsthma Chronic

Estimated

~$10 – $5,625

Children's Hospital Medical Center, CincinnatiNCT07512622